Time to progression to eGFR < 60 m/min/1.73 m
amongst those with baseline eGFR > 90 ml/min/1.73 m
. Legend: Time to development of eGFR < 60 ml/min/1.73 m2 as determined by MDRD amongst HIV positive individuals initiating Tenofovir with a baseline eGFR > 90 ml/min/1.73 m2 at IID, Pune (red) and Royal Free Hospital, UK (blue). The difference across the centres is statistically significant (p < 0.0001).