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Table 1 Demographic and epidemiological parameters on the likelihood of developing pneumococcal diseases in people over 50 years in Colombia, 2012

From: Cost-effectiveness analysis of pneumococcal conjugate vaccine 13-valent in older adults in Colombia

Parameter Mean value Data distribution Reference
Population distribution   No variation [31]
50 – 64 years 5′963,690   
65 – 74 years 1′987,534   
75 – 79 years 641,029   
80 – 99 years 630,983   
Discount rate 3% No variation Assumption
Vaccination coverage 70% Beta Assumption
Epidemiological parameters:
Incidence of bacteremia:   Beta [24]
50-64 years 0.0667%   
≥ 65 years 0.181%   
Incidence of meningitis: Beta [24, 25]
50-64 years 0.0046%   
≥ 65 years 0.0114%   
Incidence of all-cause pneumonia: Beta [24, 25]
50-64 years 0.3281%   
≥ 65 years 2.1627%   
Bacteremia mortality: Beta [23, 31]
50 – 64 years 3.5%   
65 – 74 years 5.7%   
75 – 84 years 11.4%   
85 – 99 years 27.5%   
Meningitis mortality: Beta [23, 31]
50 – 64 years 26.7%   
65 – 74 years 19.5%   
75 – 84 years 37.4%   
85 – 99 years 40.0%   
Inpatient pneumonia mortality: Beta [23, 31]
50 – 64 years 0.9%   
65 – 74 years 2.9%   
75 – 84 years 6.2%   
85 – 99 years 14.6%   
Costs (U.S. $)
Inpatient pneumonia Mean (SD)   
50 – 64 years 1,765 (4,005) Gamma Sura EPS (local data)
65 – 74 years 1,932 (4,721)   
75 – 79 years 2,688 (12,332)   
80 – 99 years 1,309 (3,355)   
Bacteremia
50 – 64 years 10,434 (16,835) Gamma Sura EPS (local data)
65 – 74 years 8,495 (10,782)   
75 – 79 years 6,753 (10,380)   
80 – 99 years 4,849 (9,772)   
Meningitis
50 – 64 years 7,789 (8,114) Gamma Sura EPS (local data)
65 – 74 years 7,783 (8,025)   
75 – 79 years 7,783 (8,025)   
80 – 99 years 7,783 (8,025)