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Table 1 Demographic and epidemiological parameters on the likelihood of developing pneumococcal diseases in people over 50 years in Colombia, 2012

From: Cost-effectiveness analysis of pneumococcal conjugate vaccine 13-valent in older adults in Colombia

Parameter

Mean value

Data distribution

Reference

Population distribution

 

No variation

[31]

50 – 64 years

5′963,690

  

65 – 74 years

1′987,534

  

75 – 79 years

641,029

  

80 – 99 years

630,983

  

Discount rate

3%

No variation

Assumption

Vaccination coverage

70%

Beta

Assumption

Epidemiological parameters:

Incidence of bacteremia:

 

Beta

[24]

50-64 years

0.0667%

  

≥ 65 years

0.181%

  

Incidence of meningitis:

Beta

[24, 25]

50-64 years

0.0046%

  

≥ 65 years

0.0114%

  

Incidence of all-cause pneumonia:

Beta

[24, 25]

50-64 years

0.3281%

  

≥ 65 years

2.1627%

  

Bacteremia mortality:

Beta

[23, 31]

50 – 64 years

3.5%

  

65 – 74 years

5.7%

  

75 – 84 years

11.4%

  

85 – 99 years

27.5%

  

Meningitis mortality:

Beta

[23, 31]

50 – 64 years

26.7%

  

65 – 74 years

19.5%

  

75 – 84 years

37.4%

  

85 – 99 years

40.0%

  

Inpatient pneumonia mortality:

Beta

[23, 31]

50 – 64 years

0.9%

  

65 – 74 years

2.9%

  

75 – 84 years

6.2%

  

85 – 99 years

14.6%

  

Costs (U.S. $)

Inpatient pneumonia

Mean (SD)

  

50 – 64 years

1,765 (4,005)

Gamma

Sura EPS (local data)

65 – 74 years

1,932 (4,721)

  

75 – 79 years

2,688 (12,332)

  

80 – 99 years

1,309 (3,355)

  

Bacteremia

50 – 64 years

10,434 (16,835)

Gamma

Sura EPS (local data)

65 – 74 years

8,495 (10,782)

  

75 – 79 years

6,753 (10,380)

  

80 – 99 years

4,849 (9,772)

  

Meningitis

50 – 64 years

7,789 (8,114)

Gamma

Sura EPS (local data)

65 – 74 years

7,783 (8,025)

  

75 – 79 years

7,783 (8,025)

  

80 – 99 years

7,783 (8,025)