Table 2 Age-specific incidence rates of bacteremia for individuals previously discharged with a COPD diagnosis and reference individuals from the general population
COPD-patients | Control Subjects | ||||
|---|---|---|---|---|---|
Pathogen | N (%)1 | Incidence2 | N (%)1 | Incidence2 | HR (95% CI)3 |
Pooled bloodstream infections | 1,265(100) | 145.0 (137.2-153.2) | 872 (100) | 62.3 (58.3-66.5) | 2.5 (2.2-2.7) |
40-59 years | 157 (12.4) | 87.4 (74.8-102.2) | 68 (7.8) | 29.1 (22.9-36.9) | 3.1 (2.2-4.3) |
60-79 years | 850 (67.2) | 154.0 (144.0-164.7) | 573 (65.7) | 61.5 (56.7-66.8) | 2.6 (2.3-3.0) |
≥80 years | 258 (20.4) | 183.0 (162.0-206.8) | 231 (26.5) | 98.2 (86.3-111.7) | 1.9 (1.5-2.3) |
Staphylococcus aureus | 183 (13.5) | 21.0 (18.1-24.2) | 127(12.8) | 9.1 (7.7-10.8) | 2.4(1.8-2.9) |
Streptococcus pneumoniae | 157 (11.2) | 18.0 (15.4-21.0) | 60(6.1) | 4.3 (3.3-5.5) | 4.1 (3.0-5.7) |
Pseudomonas aeruginosa | 45 (3.2) | 5.2 (3.9-6.9) | 26 (3.0) | 1.9 (1.3-2.7) | 3.0 (1.8-5.2) |
Enterobacteriacea 4 | 985 (42.0) | 112.9 (106.0-120.2) | 786 (48.5) | 56.2 (52.3-60.2) | 2.1 (1.9-2.5) |
Enterococci | 94 (7.2) | 10.8 (8.8-13.1) | 74 (8.2) | 5.3 (4.2-6.6) | 1.9 (1.3-2.6) |
Streptococcus pyogenes | 22 (1.6) | 2.5 (1.7-3.8) | 15 (1.6) | 1.1 (0.6-1.8) | 2.8 (1.4-5.6)5 |
Haemophilus influenzae | 10 (0.7) | 1.1 (0.6-2.1) | 7 (0.7) | 0.5 (0.2-1-0) | 2.8 (1.0-7.7)5 |
Moraxella catarrhalis | 1 | NA | 0 | NA | NA |