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Table 2 Risk factors associated with 14-day mortality in patients with P. aeruginosa bacteremia

From: Risk factors for mortality in patients with Pseudomonas aeruginosa bacteremia; retrospective study of impact of combination antimicrobial therapy

  Univariate analysis Multivariate analysis
Risk factor OR 95% CI Pvalue OR 95% CI Pvalue
Age > 60 (years) 1.42 0.77-2.64 0.26    
Neutropenia 2.14 1.09-4.22 0.03 1.45 0.63-3.33 0.37
Mechanical ventilator 8.85 3.94-19.88 0.0001 6.93 2.64-18.11 0.0001
Central venous catheter 4.46 2.29-8.67 0.0001 2.95 1.35-6.43 0.007
APACHE II score ≥ 13 8.88 4.06-19.38 0.0001 4.65 1.95-11.04 0.0001
Septic shock 5.08 2.63-9.83 0.0001 2.91 1.33-6.38 0.007
Carbapenem resistance 1.02 0.55-1.89 0.94    
Multidrug resistance 3.65 0.72-18.67 0.12    
Pneumonia as a source of bacteremia 1.01 0.51-2.01 0.96    
Empirical therapy       
 Appropriate combination therapy 0.82 0.31-2.14 0.69    
 Appropriate monotherapy 1.17 0.59-2.28 0.64    
Inappropriate therapy 1.0 (ref)      
Targeted therapy       
 Appropriate combination therapy 0.44 0.37-1.61 0.49    
 Appropriate monotherapy 0.78 0.15-1.27 0.13    
Inappropriate therapy 1.0 (ref)      
  1. OR = odd rations; CI = confidential interval; CR = carbapenem-resistance.