|
Univariate analysis
|
Multivariate analysis
|
---|
Risk factor
|
OR
|
95% CI
|
Pvalue
|
OR
|
95% CI
|
Pvalue
|
---|
Age > 60 (years)
|
1.42
|
0.77-2.64
|
0.26
| | | |
Neutropenia
|
2.14
|
1.09-4.22
|
0.03
|
1.45
|
0.63-3.33
|
0.37
|
Mechanical ventilator
|
8.85
|
3.94-19.88
|
0.0001
|
6.93
|
2.64-18.11
|
0.0001
|
Central venous catheter
|
4.46
|
2.29-8.67
|
0.0001
|
2.95
|
1.35-6.43
|
0.007
|
APACHE II score ≥ 13
|
8.88
|
4.06-19.38
|
0.0001
|
4.65
|
1.95-11.04
|
0.0001
|
Septic shock
|
5.08
|
2.63-9.83
|
0.0001
|
2.91
|
1.33-6.38
|
0.007
|
Carbapenem resistance
|
1.02
|
0.55-1.89
|
0.94
| | | |
Multidrug resistance
|
3.65
|
0.72-18.67
|
0.12
| | | |
Pneumonia as a source of bacteremia
|
1.01
|
0.51-2.01
|
0.96
| | | |
Empirical therapy
| | | | | | |
Appropriate combination therapy
|
0.82
|
0.31-2.14
|
0.69
| | | |
Appropriate monotherapy
|
1.17
|
0.59-2.28
|
0.64
| | | |
Inappropriate therapy
|
1.0 (ref)
| | | | | |
Targeted therapy
| | | | | | |
Appropriate combination therapy
|
0.44
|
0.37-1.61
|
0.49
| | | |
Appropriate monotherapy
|
0.78
|
0.15-1.27
|
0.13
| | | |
Inappropriate therapy
|
1.0 (ref)
| | | | | |
-
OR = odd rations; CI = confidential interval; CR = carbapenem-resistance.