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Table 4 Polymorphisms at known drug resistance positions of HIV-1 subtype B among chronically infected patients from Northwest Ethiopia (N = 160)

From: Clade homogeneity and Pol gene polymorphisms in chronically HIV-1 infected antiretroviral treatment naive patients after the roll out of ART in Ethiopia

Drug class

Polymorphisms

Number of cases

Frequency (%)

NRTI

 

16

10.0

 

M41R/N

2/1

1.9

 

D67E/G/K

1/1/1

1.9

 

Q151P/Q/R

1/1

1.3

 

M184L/M

4

2.5

 

T215A/P/T

3/1

2.5

NNRTI

 

52

33.5

 

A98S/Q

38/1

24.4

 

L100V

1

0.6

 

K101R/X

3/1

2.5

 

K103E/R

2

1.3

 

V108T

1

0.6

 

E138Y/D

1/1

1.3

 

G190 D/R

1/1

1.3

PR

 

11

6.9

 

V32A/V

1

0.6

 

L10I

3

1.9

 

L10V

2

1.3

 

L10L/R

1

0.6

 

V11I/V

1

0.6

 

V11F/V

1

0.6

 

V11G/V

1

0.6

 

F53L

1

0.6

  1. Keys: Numbers correspond to amino acid positions. The first letter corresponds to the wild-type amino acid; the substituted amino acid is coded by the last letter.
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BMC Infectious Diseases

ISSN: 1471-2334

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