Skip to main content

Table 3 Resistance conferring mutations in the RT gene among chronically infected patients from Northwest Ethiopia

From: Clade homogeneity and Pol gene polymorphisms in chronically HIV-1 infected antiretroviral treatment naive patients after the roll out of ART in Ethiopia

  NRTI NNRTI
Lab no Age/Sex HIV load* Mutation Resistance to Mutation Resistance to
5479 25 yrs/f 5.44 - - E138G ETR
5480 35 yrs/f 4.20 - - Y188H ETR, DLV, EFV, NVP
5905 35 yrs/f 4.58 K219E AZT, D4T, ABC, DDI, TDF - -
5496 30 yrs/f 3.88 L210W AZT, D4T - -
5489 28 yrs/f 5.76 - - E138G ETR
5520 35 yrs/f 5.49 - - E138A ETR
5616 30 yrs/f 4.31 K65R ABC, ddI, FTC, 3TC, d4T, TDF - -
5652 40 yrs/f 5.50 - - E138A ETR
5763 45 yrs/f 4.91 - - E138A ETR
5843 27 yrs/f 4.49 - - E138A ETR
5501 27 yrs/f 4.38 - - V90I ETR
5604 44 yrs/f 4.64 - - V90I ETR
5491 25 yrs/m 5.94 - - K101E, E138A DLV, EFV, ETR, NVP
5533 32 yrs/m 5.17 - - G190A EFV, ETR, NVP, RPV
5566 30 yrs/m 5.49 - - E138A ETR
5711 22 yrs/m 5.13 - - E138A ETR
5727 35 yrs/m 4.80 - - E138A ETR
5712 28 yrs/m 4.82 - - G190A EFV, ETR, NVP, RPV
5710 38 yrs/m 5.17 L210W AZT, D4T - -
5603 22 yrs/m 5.12 - -   V90I ETR
5991 24 yrs/m 4.36 - - M230I RPV
  1. *HIV load in log10 copies/ml; Mutations in bold are only considered by both IAS and Stanford University HIV drug resistance algorithm; Mutation in Italics are reported by IAS only.
  2. Abreviations: 3TC lamiduvine, ddI didanosine, d4T stavudine, FTC emtricitabine, TDF tenofovir, ZDV zidovudine, NNRTI non-nucleoside RT inhibitors, DLV delavirdine, EFV efavirenz, ETR etravirine, NVP nevirapine, RPV rilpivirine.