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Table 3 Resistance conferring mutations in the RT gene among chronically infected patients from Northwest Ethiopia

From: Clade homogeneity and Pol gene polymorphisms in chronically HIV-1 infected antiretroviral treatment naive patients after the roll out of ART in Ethiopia

 

NRTI

NNRTI

Lab no

Age/Sex

HIV load*

Mutation

Resistance to

Mutation

Resistance to

5479

25 yrs/f

5.44

-

-

E138G

ETR

5480

35 yrs/f

4.20

-

-

Y188H

ETR, DLV, EFV, NVP

5905

35 yrs/f

4.58

K219E

AZT, D4T, ABC, DDI, TDF

-

-

5496

30 yrs/f

3.88

L210W

AZT, D4T

-

-

5489

28 yrs/f

5.76

-

-

E138G

ETR

5520

35 yrs/f

5.49

-

-

E138A

ETR

5616

30 yrs/f

4.31

K65R

ABC, ddI, FTC, 3TC, d4T, TDF

-

-

5652

40 yrs/f

5.50

-

-

E138A

ETR

5763

45 yrs/f

4.91

-

-

E138A

ETR

5843

27 yrs/f

4.49

-

-

E138A

ETR

5501

27 yrs/f

4.38

-

-

V90I

ETR

5604

44 yrs/f

4.64

-

-

V90I

ETR

5491

25 yrs/m

5.94

-

-

K101E, E138A

DLV, EFV, ETR, NVP

5533

32 yrs/m

5.17

-

-

G190A

EFV, ETR, NVP, RPV

5566

30 yrs/m

5.49

-

-

E138A

ETR

5711

22 yrs/m

5.13

-

-

E138A

ETR

5727

35 yrs/m

4.80

-

-

E138A

ETR

5712

28 yrs/m

4.82

-

-

G190A

EFV, ETR, NVP, RPV

5710

38 yrs/m

5.17

L210W

AZT, D4T

-

-

5603

22 yrs/m

5.12

-

-

 

V90I ETR

5991

24 yrs/m

4.36

-

-

M230I

RPV

  1. *HIV load in log10 copies/ml; Mutations in bold are only considered by both IAS and Stanford University HIV drug resistance algorithm; Mutation in Italics are reported by IAS only.
  2. Abreviations: 3TC lamiduvine, ddI didanosine, d4T stavudine, FTC emtricitabine, TDF tenofovir, ZDV zidovudine, NNRTI non-nucleoside RT inhibitors, DLV delavirdine, EFV efavirenz, ETR etravirine, NVP nevirapine, RPV rilpivirine.
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BMC Infectious Diseases

ISSN: 1471-2334

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