Table 2 SIRS and Sepsis Definition (ACCP/SCCM criteria)
SIRS systemic inflammatory response syndrome | Sepsis | Severe sepsis | Septic shock |
|---|---|---|---|
Two or more of the following criteria: | Documented infection together with 2 or more SIRS criteria. | Sepsis-induced tissue hypoperfusion or organ dysfunction, including hypotension, lactic acidosis, oliguria, hypoxemia, coagulation disorders and acute alteration in mental status. | Sepsis with hypotension, despite adequate fluid resuscitation, along with the presence of perfusion abnormalities. |
• Temperature > 38°C or <36°C | |||
• Heart rate > 90/min | |||
• Respiratory rate > 20/min or PaCO 2 < 32 mmHg (4.3 kPa) | |||
• WBC > 12 × 109 /L, < 4 × 109/L, or > 10% immature forms |