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Table 3 Predictors of death: univariate and multivariate analysis

From: Clinical and immunological outcomes according to adherence to first-line HAART in a urban and rural cohort of HIV-infected patients in Burkina Faso, West Africa

   Univariate analysis Multivariate analysis
  Variables HR 95% IC p value HR 95% IC p value
Center CERBA vs CMSC 4.98 2.19 – 11.32 <0.001 2.76 1.15 – 6.65 0.024
Nanoro vs CMSC 8.08 3.35 – 19.49 <0.001 10.60 3.78 – 29.75 0.001
Sex M vs F 1.44 0.83 – 2.51 0.21    
Religion Muslim vs Christian 0.90 0.52 – 1.54 0.69    
Living area Rural vs Urban. 2.12 1.24 – 3.64 0.008 - - -
HIV type infection 2 vs 1 1.29 0.18 – 9.38 0.80    
Mixed vs 1 2.31 0.92 – 5.78 0.075    
Literacy Illiterate vs literate 1.29 0.75 – 2.23 0.36    
Age 1 year increase 1.32 0.98 – 1.79 0.076    
CD4+ T-cell count at baseline ≤50 vs >50 1.53 0.74 – 3.17 0.28    
WHO HIV clinical stage$ Early vs advanced 0.5 0.29 – 0.88 0.016 - - -
HAART regimen including FDC No vs Yes 2.70 1.58 – 4.59 < 0.001 0.40 0.22 – 0.70 <0.001
Increasing adherence score For 1 point increasing 0.60 0.47 – 0.76 <0.001 0.87 0.81 – 0.93 <0.001
8–10 vs 0–7 0.37 0.21 – 0.63 <0.001 0.32 0.18 – 0.57 <0.001
Calendar year*$ - - - 0.008 - - -
  1. Notes: HR: hazard ratio; CI: confidence interval; CERBA: “Pietro Annigoni” Biomolecular Research Center; CMSC: Centre Médicale Saint Camille, Ougadougou; HAART: highly active antiretroviral therapy; FDC: fixed dose combination.
  2. *For Calendar Year only p-value for likelihood-ratio test (model with/without variable) reported.
  3. $Variables included in the model as strata.
  4. §p-values below 0.05 (in boldface) were considered to be significant.