Skip to main content

Table 3 Predictors of death: univariate and multivariate analysis

From: Clinical and immunological outcomes according to adherence to first-line HAART in a urban and rural cohort of HIV-infected patients in Burkina Faso, West Africa

  

Univariate analysis

Multivariate analysis

 

Variables

HR

95% IC

p value

HR

95% IC

p value

Center

CERBA vs CMSC

4.98

2.19 – 11.32

<0.001

2.76

1.15 – 6.65

0.024

Nanoro vs CMSC

8.08

3.35 – 19.49

<0.001

10.60

3.78 – 29.75

0.001

Sex

M vs F

1.44

0.83 – 2.51

0.21

   

Religion

Muslim vs Christian

0.90

0.52 – 1.54

0.69

   

Living area

Rural vs Urban.

2.12

1.24 – 3.64

0.008

-

-

-

HIV type infection

2 vs 1

1.29

0.18 – 9.38

0.80

   

Mixed vs 1

2.31

0.92 – 5.78

0.075

   

Literacy

Illiterate vs literate

1.29

0.75 – 2.23

0.36

   

Age

1 year increase

1.32

0.98 – 1.79

0.076

   

CD4+ T-cell count at baseline

≤50 vs >50

1.53

0.74 – 3.17

0.28

   

WHO HIV clinical stage$

Early vs advanced

0.5

0.29 – 0.88

0.016

-

-

-

HAART regimen including FDC

No vs Yes

2.70

1.58 – 4.59

< 0.001

0.40

0.22 – 0.70

<0.001

Increasing adherence score

For 1 point increasing

0.60

0.47 – 0.76

<0.001

0.87

0.81 – 0.93

<0.001

8–10 vs 0–7

0.37

0.21 – 0.63

<0.001

0.32

0.18 – 0.57

<0.001

Calendar year*$

-

-

-

0.008

-

-

-

  1. Notes: HR: hazard ratio; CI: confidence interval; CERBA: “Pietro Annigoni” Biomolecular Research Center; CMSC: Centre Médicale Saint Camille, Ougadougou; HAART: highly active antiretroviral therapy; FDC: fixed dose combination.
  2. *For Calendar Year only p-value for likelihood-ratio test (model with/without variable) reported.
  3. $Variables included in the model as strata.
  4. §p-values below 0.05 (in boldface) were considered to be significant.