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Table 4 Univariate and multivariate logistic regression analysis to identify factors potentially associated with ribavirin underexposure (defined by an AUC < 1755 μg.h/L)

From: Lower ribavirin biodisponibility in patients with HIV-HCV coinfection in comparison with HCV monoinfected patients

  Univariate analysis   Multivariate analysis  
  OR (95% CI) p OR (95% CI) p
HIV coinfection (yes vs no) 3.34 (1.24-9.01) 0.017 3.76 (1.21-11.6) 0.022
Gender (male vs female) 7.00 (1.89-25.9) 0.004 4.59 (1.15-18.3) 0.031
Weight 1.03 (0.99-1.06) 0.067 1.03 (0.99-1.08) 0.142
Age 0.97 (0.93-1.01) 0.160 - -
MDRD 1.00 (0.98-1.02) 0.803 - -
Cockroft 1.01 (0.99-1.02) 0.145 1.00 (0.98-1.02) 0.927
  1. Bold style indicates statistical significance.