Table 4 Univariate and multivariate logistic regression analysis to identify factors potentially associated with ribavirin underexposure (defined by an AUC < 1755 μg.h/L)
Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
OR (95% CI) | p | OR (95% CI) | p | |
HIV coinfection (yes vs no) | 3.34 (1.24-9.01) | 0.017 | 3.76 (1.21-11.6) | 0.022 |
Gender (male vs female) | 7.00 (1.89-25.9) | 0.004 | 4.59 (1.15-18.3) | 0.031 |
Weight | 1.03 (0.99-1.06) | 0.067 | 1.03 (0.99-1.08) | 0.142 |
Age | 0.97 (0.93-1.01) | 0.160 | - | - |
MDRD | 1.00 (0.98-1.02) | 0.803 | - | - |
Cockroft | 1.01 (0.99-1.02) | 0.145 | 1.00 (0.98-1.02) | 0.927 |