Predictor variable
|
Patients never started cART*
|
Patients on cART†
|
---|
|
HR [95% CI]
|
Pvalue
|
HR [95% CI]
|
Pvalue
|
---|
Gender
| | | | |
Female
|
1
| |
1
| |
Male
|
0.73 [0.36-1.47]
|
0.38 (NS)
|
1.49 [0.84- 2.62]
|
0.17 (NS)
|
Median age, years
| | | | |
≤38
|
1
| |
1
| |
>38
|
0.86 [0.47-1.58]
|
0.62 (NS)
|
1.42 0.89 2.27
|
0.14 (NS)
|
Region of origin
| | | | |
Germany
|
1
| |
1
| |
Sub-Saharan Africa
|
4.05 [1.87-8.78]
|
<0.001
|
5.15 [2.76-9.60]
|
<0.001
|
Other countries
|
1.75 [0.81-38.1]
|
0.16
|
2.22 [1.18-4.20]
|
0.014
|
HIV-transmission risk group
| | | | |
Others†
|
1
| |
1
| |
MSM
|
0.68 [0.31-1.51]
|
0.34
|
0.60 [0.32-1.10]
|
0.10 (NS)
|
CD4+ cell count (cells/μl)
| | | | |
≥200
|
1
| |
1
| |
<200
|
8.22 [4.36-15.51]
|
<0.001
|
1.90 [1.14-3.15]
|
0.013
|
Viral load (log10 copies/ml)
| | | | |
< 5
|
1
| |
1
| |
≥ 5
|
2.51 [1.33-4.75]
|
0.005
|
1.77 [1.11-2.82]
|
0.016
|
- HR, hazard ratio; CI, confidence interval; NS, non-significant; MSM, men who have sex with men.
- *50 TB cases among 1,919 subjects. †78 TB cases among 6,357 subjects.
-
†Others included heterosexual, blood transfusion and mother to child transmission.