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Table 4 Cox proportional hazards analysis of factors associated with TB among people living with HIV/AIDS in the ClinSurv HIV Cohort, Germany 2001–2011

From: Tuberculosis among people living with HIV/AIDS in the German ClinSurv HIV Cohort: long-term incidence and risk factors

Predictor variable Patients never started cART* Patients on cART
  HR [95% CI] Pvalue HR [95% CI] Pvalue
Gender     
   Female 1   1  
   Male 0.73 [0.36-1.47] 0.38 (NS) 1.49 [0.84- 2.62] 0.17 (NS)
Median age, years     
   ≤38 1   1  
   >38 0.86 [0.47-1.58] 0.62 (NS) 1.42 0.89 2.27 0.14 (NS)
Region of origin     
   Germany 1   1  
   Sub-Saharan Africa 4.05 [1.87-8.78] <0.001 5.15 [2.76-9.60] <0.001
   Other countries 1.75 [0.81-38.1] 0.16 2.22 [1.18-4.20] 0.014
HIV-transmission risk group     
   Others 1   1  
   MSM 0.68 [0.31-1.51] 0.34 0.60 [0.32-1.10] 0.10 (NS)
CD4+ cell count (cells/μl)     
   ≥200 1   1  
   <200 8.22 [4.36-15.51] <0.001 1.90 [1.14-3.15] 0.013
Viral load (log10 copies/ml)     
   < 5 1   1  
   ≥ 5 2.51 [1.33-4.75] 0.005 1.77 [1.11-2.82] 0.016
  1. HR, hazard ratio; CI, confidence interval; NS, non-significant; MSM, men who have sex with men.
  2. *50 TB cases among 1,919 subjects. 78 TB cases among 6,357 subjects.
  3. Others included heterosexual, blood transfusion and mother to child transmission.