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Table 1 Demographic and clinical characteristic of people living with HIV/AIDS by cART status in the ClinSurv HIV Cohort, Germany 2001–2011

From: Tuberculosis among people living with HIV/AIDS in the German ClinSurv HIV Cohort: long-term incidence and risk factors

Characteristic Non-cART cART* Total
  N = 2,467 (21.1%) N = 9,226 (78.9%) N = 11,693 (100%)
TB patients 103 (4.2%) 130 (1.4%) 233 (2%)
Gender    
   Male 1.994 (80.8%) 7,394 (80.2%) 9,388 (80.3%)
   Female 473 (19.2%) 1,831 (19.9%) 2,304 (19.7%)
Age at enrollment, years    
Median [IQR] 35 [29–42] 39 [32–46] 38 [31–45]
   ≤38 1,468 (59.6%) 4,338 (47.1%) 5,806 (49.7%)
   >38 994 (40.4%) 4,873 (52.9%) 5,867 (50.3%)
Geographical origin    
   Germany 1,731 (72.1%) 6,631 (73.0%) 8,362 (72.8%)
   Sub-Saharan Africa 255 (10.6%) 1,066 (11.7%) 1,321 (11.5%)
HIV-transmission risk group    
   MSM 1,339 (60.3%) 4,768 (57.8%) 6,107 (58.4%)
   Other 881 (39.7%) 3,477 (42.8%) 4,358 (41.6%)
CD4+ cell count at enrollment in the cohort, cells/μl    
Median [IQR] 492 [349–663] 273 [118–453] 320 [146–508]
   >200 2,054 (89.1%) 5,467 (61.9%) 7,521 (67.6%)
   ≤200 251 (10.9%) 3,362 (38.1%) 3,613 (32.5%)
Viral load at enrollment in the cohort, log10 copies/ml    
Median [IQR] 4.2 [3.4 – 4.8] 4.5 [3.1 – 5.2] 4.4 [3.3 – 5.7]
   <5 1,769 (72.9%) 5,845 (68.1%) 7,614 (70.5%)
   ≥5 446 (20.1%) 2,737 (31.9%) 3,183 (29.5%)
Calendar year of enrollment    
   2001 147 (5.9%) 765 (8.2%) 912 (7.7%)
   2002 166 (6.7%) 832 (9.0%) 998 (8.4%)
   2003 178 (7.2%) 839 (10.1%) 1,017 (8.7%)
   2004 205 (8.3%) 928 (10.1%) 1,133 (9.7%)
   2005 213 (8.6%) 908 (9.8%) 1,121(9.5%)
   2006 225 (9.1%) 842 (9.1%) 1,067 (9.1%)
   2007 251(10.2%) 893 (10.6%) 1,144 (9.8%)
   2008 217 (8.8%) 883 (9.5%) 1,100 (9.4%)
   2009 249 (10.1%) 835 (9.1%) 1,084 (9.3%)
   2010 278 (11.3%) 811 (8.8%) 1,089 (9.3%)
   2011 338 (13.7%) 690 (7.5%) 1,028 (8.8%)
Length of follow-up (person-years)    
Median [IQR] 1.2 [0.3-2.8] 3.1 [1.3-5.9] 2.5 [1.1-5.3]
  1. cART, combination antiretroviral therapy; TB, tuberculosis; IQR; interquartile range; MSM, men who have sex with men; PWID, person who inject drugs; HPC, high HIV-prevalence countries.
  2. *cART initiated during follow-up at any time prior to TB diagnosis.
  3. Significantly associated with receiving cART (multivariable logistic regression model including all presented characteristics as independent variables; P < 0.05).
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