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Table 2 Clinical manifestations, laboratory findings and outcomes among 35 cases of listeriosis

From: Emergence of sporadic non-clustered cases of hospital-associated listeriosis among immunocompromised adults in southern Taiwan from 1992 to 2013: effect of precipitating immunosuppressive agents

  All ( n = 35) Community-associated (n = 23) Hospital-associated (n = 12) p-value
Clinical findings
APACHE II score, median (range) 15 (4–46) 12 (4–46) 19 (6–30) 0.55
Headache (%) 4 (11.4) 3 (13) 1 (8.3) 1.0
Nausea (%) 3 (8.6) 1 (4.3) 2 (16.7) 0.27
Reduced consciousness (%) 11 (31.4) 6 (26.1) 5 (41.7) 0.45
Seizure (%) 6 (17.1) 3 (13) 3 (25) 0.39
Focal neurologic (%) 3 (8.6) 2 (8.7) 1 (8.3) 1.0
Diarrhea (%) 3 (8.6) 2 (8.7) 1 (8.3) 1.0
Fever (%) 31 (88.6) 20 (87) 11 (91.7) 1.0
Adequate antibiotic therapy within 24 hours (%) 4 (11.4) 1 (4.3) 3 (25) 0.16
CNS infection (%) 10 (28.6) 8 (34.8) 2 (16.7) 0.43
60-day mortality (%) 12 (34.3) 4 (17.4) 8 (66.7) 0.01
Hospital duration, median day (range) 28 (1–126) 20 (1–124) 53 (15–126) 0.01
Laboratory findings
ALT, median IU/L (range) 41 (6–248) 47.5 (6–248) 39 (15–177) 0.88
Total bilirubin, median mg/dL (range) 0.9 (0.2–7.9) 0.8 (0.2–4) 0.5 (0.2–7.9) 0.24
Albumin, median g/dL (range) 2.7 (1.4–3.9) 2.6 (1.7–3.8) 2.4 (1.4–3.9) 0.93
White blood cells, median 109/L (range) 8.38 (0.19–28.16) 13.39 (3.36–27.47) 8.38 (0.19–28.16) 0.06
Platelets, median /mm3 (range) 117 (4–350) 158.72 (27.7–350) 101.91 (4–275) 0.18
Serum creatinine, median mg/dL (range) 1.1 (0.4–17.2) 1.10 (0.58–17.2) 1.10 (0.4–8.84) 0.07
Site of L. monocytogenes isolates     
Blood (%) 33 (94.3) 21 (91.3) 12 (100) 0.54
CSF (%) 6 (17.1) 5 (21.7) 1 (8.3) 0.64
Joint fluid (%) 1 (2.8) 1 (4.3) 0 (0) 1.0
  1. Data are no. (%) of patients, unless otherwise indicated. APACHE II, Acute Physiology And Chronic Health Evaluation II; ALT, alanine aminotransferase.