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Table 4 Quality assessment of clinical trials of oral antibiotic therapy in infective endocarditis

From: Oral antibiotic therapy for the treatment of infective endocarditis: a systematic review

 

Provides case definition for infective endocarditis

Defines eligibility criteria

Provides details of the setting and location of the study

Provides detailed description of the intervention

Details processes for ascertainment and measurement of outcomes

Provides justification for sample size

Establishes an adequate sequence generation

Allocation concealment

Blinding (study drug)

Blinding (outcomes)

Analysis of safety of the intervention

Describes participants’ flow

Addresses incompleted outcome data

Addresses risk of selective reporting

Provides information on accessibility to the study protocol, trial registration and funding for the study

Heldman et al[18]

√

√

√

√

√

√

√

X

X

X

√

√

√

√

√

Stamboulian et al[19]

√

√

√

√

X

X

X

X

X

X

X

N.A.

N.A.

N.A.

X

  1. N.A. denotes not applicable since Stamboulian et al [20] reported 100% compliance in both treatment arms.