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Table 4 Quality assessment of clinical trials of oral antibiotic therapy in infective endocarditis

From: Oral antibiotic therapy for the treatment of infective endocarditis: a systematic review

  Provides case definition for infective endocarditis Defines eligibility criteria Provides details of the setting and location of the study Provides detailed description of the intervention Details processes for ascertainment and measurement of outcomes Provides justification for sample size Establishes an adequate sequence generation Allocation concealment Blinding (study drug) Blinding (outcomes) Analysis of safety of the intervention Describes participants’ flow Addresses incompleted outcome data Addresses risk of selective reporting Provides information on accessibility to the study protocol, trial registration and funding for the study
Heldman et al[18] X X X
Stamboulian et al[19] X X X X X X X N.A. N.A. N.A. X
  1. N.A. denotes not applicable since Stamboulian et al [20] reported 100% compliance in both treatment arms.