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Table 1 Clinical and radiological characteristics of patients with positive sputum smear at the end of the second month of intensive treatment, with positive (C+) or negative (C–) culture for Mycobacterium tuberculosis

From: Non-conversion of sputum culture among patients with smear positive pulmonary tuberculosis in Cameroon: a prospective cohort study

Characteristics

Overall (n = 86)

C + (n = 46)

C– (n = 40)

p

Sex

Men, n (%)

63 (73.3)

35 (76.1)

28 (70)

0.525

Women, n (%)

23 (26.7)

11 (23.9)

12 (30)

 

Median age, years (25th-75th percentiles)

33 (26–42)

35.5 (25.8-46.5)

33 (26.3-38.8)

0.259

Age groups, years, n (%)

  33

40 (46.5)

22 (47.8)

18 (45.0)

reference

33-42

26 (30.2)

9 (19.6)

17 (42.5)

0.105

> 42

20 (23.3)

15 (32.6)

5 (12.5)

0.133

Clinical signs

Haemoptysis, n (%)

19 (22.1)

6 (13)

13 (32.5)

0.030

Dyspnoea, n (%)

24 (27.9)

11 (23.9)

13 (32.5)

0.375

Fever, n (%)

74 (86)

41 (89.1)

33 (82.5)

0.376

Weight loss, n (%)

80 (93)

43 (93.5)

37 (92.5)

0.859

Median BMI, kg/m2 (25th-75th percentiles)

19.3 (17.4-20.8)

18.9 (17.2-21.0)

19.4 (17.5-20.3)

0.698

BMI strata, kg/m2

< 18.5

18 (20.9)

11 (23.9)

7 (17.5)

0.466

≥ 18.5

35 (76.1)

35 (76.1)

33 (82.5)

 

BCG vaccination, n (%)

63 (73.3)

33 (71.7)

30 (75.0)

0.733

Diabetes mellitus, n (%)

2 (2.3)

2 (4.3)

0 (0)

0.182

Habits

Smoking, n (%)

22 (25.6)

17 (37)

5 (12.5)

0.010

Alcohol consumption, n (%)

22 (25.6)

13 (28.3)

9 (22.5)

0.541

Median symptoms duration, weeks (25th-75th percentiles)

13 (8–20.3)

12 (6–21)

13 (8–20)

0.744

HIV Positive, n (%)

24 (27.9)

11 (23.9)

13 (32.5)

0.376

Median CD4, /mm3 (25th-75th percentiles)

187 (151.3-216.3)

187 (151–240)

187 (144–210)

0.697

CD4 strata, /mm3

< 50

3/24 (12.5)

1/11 (9.1)

2/13 (15.4)

1.000

50-200

15/24 (62.5)

7/11 (63.6)

8/13 (61.5)

1.000

> 200

6/24 (25.0)

3/11 (27.3)

3/13 (23.1)

Reference

Chest X-ray

Number of affected areas > 4, n (%)

46 (53.5)

28 (60.9)

18 (45.0)

0.141

Presence of cavitations, n (%)

60 (69.8)

31 (67.4)

29 (72.5)

0.607

  1. C+, positive culture for Mycobacterium tuberculosis; C– , negative culture for Mycobacterium tuberculosis; BMI, body mass index.