Skip to main content

Table 4 Evaluation of different treatment strategies based on local epidemiology and on the results of rapid urine test (RUT) in a cohort of 346 patients with symptoms of acute uncomplicated cystitis

From: Antibiotic treatment of acute uncomplicated cystitis based on rapid urine test and local epidemiology: lessons from a primary care series

  Antibiotic (ATB) Treatment strategy
  ATB for all symptomatic patients (i.e.no RUT used) ATB only in patients with positive RUTa  
Patients treated (%) 347 (100) 311 (89)  
Appropriate ATB decision b (%) 253 (73) 278 (80) 0.02d
No ATB, negative UCc 0 31
ATB, positive UC 253 247
Inappropriate ATB decision (%) 94 (27%) 70 (20%)
ATB, negative UC 94 64
No ATB, positive UC 0 6  
Overall susceptibility rates according to the ATB regimen e (%)    
Fosfomycin 89 90
Nitrofurantoin 98 98
TMP-SMX 85 86
Ofloxacin 94 95
Pivmecillinam 76 78
Fosfomycin, except if RUT-   
For nitrites and age < 30: nitrofurantoin   93
Fosfomycin, except if RUT-   
For nitrites and age < 30: ofloxacin   93
  1. aRUT considered positive when leukocytes and/or nitrites were detected.
  2. bATB decision considered appropriate or not according to the results of urine analysis.
  3. cUC: urine culture.
  4. dNB: p = 0.02 when appropriate and inappropriate ATB decision were compared using standard thresholds, and p = 0.03 using reduced thresholds.
  5. eSusceptibility rate for patients with a positive urine culture.