Strain | Previous vaccination† | Time point | SPR | SCR | MGI | |||
---|---|---|---|---|---|---|---|---|
n/N (%; 95% CI) | n/N (%; 95% CI) | N; value (95% CI) | ||||||
18–60 years | >60 years | 18–60 years | >60 years | 18–60 years | >60 years | |||
A/H1N1 | Yes | Day 0 | 13/20 | 19/44 | – | – | – | – |
(65.0; 40.8–84.6) | (43.2; 28.3–59.0) | |||||||
Day 21 | 20/20 | 41/44 | 13/20 | 31/44 | 20; 7.1 | 44; 6.8 | ||
(100; 83.2–100) | (93.2; 81.3–98.6) | (65.0; 40.8–84.6) | (70.5; 54.8–83.2) | (3.5– 14.3) | (4.7–9.8) | |||
No | Day 0 | 16/29 | 3/26 | – | – | – | – | |
(55.2; 35.7–73.6) | (11.5; 2.4–30.2) | |||||||
Day 21 | 29/29 | 21/26 | 22/29 | 19/26 | 29; 12.6 | 26; 16.0 | ||
(100; 88.1–100) | (80.8; 60.6–93.4) | (75.9; 56.5–89.7) | (73.1; 52.2–88.4) | (6.8– 23.3) | (9.4–27.3) | |||
A/H3N2 | Yes | Day 0 | 8/20 | 15/44 | – | – | – | – |
(40.0; 19.1–63.9) | (34.1; 20.5–49.9) | |||||||
Day 21 | 20/20 | 43/44 | 15/20 | 35/44 | 20; 8.9 | 44; 9.9 | ||
(100; 83.2–100) | (97.7; 88.0–99.9) | (75.0; 50.9–91.3) | (79.5; 64.7–90.2) | (4.7– 16.8) | (6.7–14.7) | |||
No | Day 0 | 7/29 | 2/26 | – | – | – | – | |
(24.1; 10.3–43.5) | (7.7; 0.9–25.1) | |||||||
Day 21 | 28/29 | 22/26 | 26/29 | 22/26 | 29; 17.2 | 26; 25.8 | ||
(96.6; 82.2–99.9) | (84.6; 65.1–95.6) | (89.7; 72.6–97.8) | (84.6; 65.1–95.6) | (11.8–25.1) | (15.7–42.5) | |||
B strain (Victoria) | Yes | Day 0 | 12/20 | 27/44 | – | – | ||
(60.0; 36.1–80.9) | (61.4; 45.5–75.6) | |||||||
Day 21 | 20/20 | 44/44 | 10/20 | 27/44 | 20; 5.3 | 44; 5.0 | ||
(100; 83.2–100) | (100; 92.0–100) | (50.0; 27.2–72.8) | (61.4; 45.5–75.6) | (2.7– 10.4) | (3.5–7.0) | |||
No | Day 0 | 9/29 | 8/26 | – | – | |||
(31.0; 15.3–50.8) | (30.8; 14.3–51.8) | |||||||
Day 21 | 27/29 | 25/26 | 23/29 | 24/26 | 29; 19.6 | 26; 23.9 | ||
(93.1; 77.2–99.2) | (96.2; 80.4–99.9) | (79.3; 60.3–92.0) | (92.3; 74.9–99.1) | (10.3– 37.2) | (14.0–40.6) |