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Table 4 Predictors of 30-day all-cause mortality among patients with community-onset bloodstream infection

From: Community-onset bloodstream infection with multidrug-resistant organisms: a matched case-control study

Variable Patients who died in 30 days Patients who survived Univariate analysis Multivariate analysis
  n = 46 n = 314 OR (95% CI) P value AOR (95% CI) P value
Age, mean (SD), years 74.8 (16.3) 63.1 (19.9) 1.04 (1.02-1.06) <0.001a 1.04 (1.02-1.06) <0.001
Male, no (%) 31 (67.4) 186 (59.2) 1.42 (0.74-2.74) 0.29   
Residence in LTCF, no (%) 18 (39.1) 56 (17.8) 2.96 (1.53-5.72) 0.001a   
Charlson co-morbidity index, mean (SD) 3.5 (2.2) 2.6 (2.4) 1.15 (1.02-1.30) 0.018a   
Acquisition-healthcare associated, no (%) 35 (76.1) 185 (58.9) 2.22 (1.09-4.53) 0.029a   
Underlying immunosuppression, no (%) 14 (30.4) 98 (31.2) 0.96 (0.49-1.89) 0.92   
High risk BSI sourcesb, no (%) 30 (65.2) 153 (48.7) 1.97 (1.03-3.76) 0.039a 2.30 (1.16-4.57) 0.02
Pitt bacteraemia score, median (IQR) 2 (1-4) 1 (0-2) 1.39 (1.18-1.64) <0.001a 1.36 (1.15-1.61) <0.001
Severe sepsis or septic shock, no (%) 13 (28.3) 38(12.1) 2.86 (1.39-5.91) 0.005c   
ICU admission, no (%) 12 (26.1) 51 (16.2) 1.82 (0.88-3.75) 0.11   
Bacteraemia due to MDR organisms, no (%) 28 (60.9) 152 (48.4) 1.66 (0.88-3.12) 0.12   
Inactive empiric antibiotic, no (%) 16 (34.8) 61 (19.4) 2.21 (1.13-4.31) 0.02a   
  1. NOTE. OR, odds ratio; AOR, adjusted odds ratio; CI, confidence interval; SD, standard deviation; IQR, interquartile range; LTCF, long-term care facility; BSI, bloodstream infections; ICU, intensive care unit; MDR, multidrug-resistant.
  2. aVariables eligible for inclusion in the multivariate analysis.
  3. bHigh risk sources refer to BSI secondary to respiratory, gastrointestinal, hepatobiliary, bone and joint, cardiovascular or unidentified sources.
  4. cPairwise correlation >0.7 with Pitt bacteraemia score.