Glutathione S-transferase L1 multiplex serology as a measure of cumulative infection with human papillomavirus

BMC Infectious Diseases

Table 1 Sampling-adjusted data describing antibody levels measured by the GST-L1 assay among HPV-unvaccinated women in the Costa Rica Vaccine Trial

HPV type		Min (MFI)	Max (MFI)	Geometric mean (MFI)	Q1* (MFI)	Q2*, median (MFI)	Q3* (MFI)
HPV 16	All women (N = 2,786)	0	5979	19	5	30	67
	Seropositive women (N = 140)	415	5979	902	570	777	1329
	HPV16 infection (N = 211)	0	1709	28	8	40	104
	No HPV16 infection (N = 2575)	0	5979	18	5	30	66
HPV18	All women (N = 2,979)	0	2849	17	3	26	57
	Seropositive women (N = 155)	416	2849	677	528	528	930
	HPV18 infection (N = 196)	0	2696	17	9	24	33
	No HPV18 infection (N = 2783)	0	2849	17	3	26	57

*Q1, Q2, and Q3 refer to the first, second, and third quartiles, respectively, of the sampling-adjusted distribution of antibody levels.
“Infection” refers to incident infection over 4 years of follow-up. Analyses are based on 467 women for HPV16 and 477 women for HPV18; displayed sample sizes are sampling-adjusted.

ISSN: 1471-2334