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Table 2 Comparison of sample collection yield among patients culture-positive for M. tuberculosis by any collection method

From: Intensified specimen collection to improve tuberculosis diagnosis in children from Rural South Africa, an observational study

TB status* Sputum smear Sputum culture Gastric smear Gastric culture** Blood Urine DST interpretation*** Age (years) HIV status CD4%
Possible - + - + - - DS 1.3 Negative n/a
Possible - + + + - - DS 2.2 Negative n/a
Possible - + - - - - DS 1.7 Positive 5.3
Possible - - NC NC - + MDR 8.3 Positive 17.4
Probable - + - + - NC DS 2.0 Negative n/a
Probable - + + + + - DS 1.5 Negative n/a
Probable + + NC NC + + DS 7.0 Positive 2.6
Probable + + + + + + XDR 11 Positive 10.9
Total positive (% of collected) 2 (25) 7 (88) 3 (50) 5 (83) 3 (38) 3 (43)     
  1. *TB status prior to obtaining microbiologic confirmation.
  2. **Among the subjects who had positive cultures by gastric aspirates, 4 (80%) demonstrated culture-positivity from all three aspirates while 1 (20%) child only demonstrated culture-positivity from the first two aspirates and left the hospital prior to collection of the third aspirate.
  3. ***DST: drug susceptibility testing.
  4. XDR: extensively drug-resistant tuberculosis. DS: drug susceptible. MDR: multi-drug resistant. NC: not collected.
  5. n/a: not applicable.