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Table 2 Overall sensitivity, specificity and negative and positive predictive value of the three RDTs evaluated against microscopy, and microscopy and PCR

From: Performance of Paracheck™-Pf, SD Bioline malaria Ag-Pf and SD Bioline malaria Ag-Pf/pan for diagnosis of falciparum malaria in the Central African Republic

  Reference Sensitivity Specificity Positive predictive value Negative predictive value
   [95% CI] [95% CI] [95% CI] [95% CI]
Paracheck™-Pf Microscopy 85.9 [80.8-90.1] 86.6 [81.1-91.0] 88.2 [83.2-92.1] 84.1 [78.4-88.8]
Microscopy and PCR 85.7 [80.8–89.8] 86.0 [80.1–90.6] 89.3 [84.7-92.9] 81.5 [75.4-86.7]
SD Bioline AgPf Microscopy 92.3 [88.1-95.4] 82.2 [76.2-87.2] 85.7 [80.8-89.8] 90.2 [85.0-94.1]
Microscopy and PCR 85.4 [80.5–90.7] 86.3 [80.5–9.7] 89.7 [85.1-93.2] 81.0 [74.8-86.3]
SD Bioline AgPf/Pan Microscopy 92.3 [88.1-95.4] 81.2 [81.1-91.0] 85.0 [80.0-89.2] 90.1 [84.8-94.0]
  Microscopy and PCR 88.2 [83.2–92.0%] 80.4 [74.3–85.5] 83.1 [77.7-87.6] 86.1 [80.5-90.7]