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Table 2 Overall sensitivity, specificity and negative and positive predictive value of the three RDTs evaluated against microscopy, and microscopy and PCR

From: Performance of Paracheck™-Pf, SD Bioline malaria Ag-Pf and SD Bioline malaria Ag-Pf/pan for diagnosis of falciparum malaria in the Central African Republic

 

Reference

Sensitivity

Specificity

Positive predictive value

Negative predictive value

  

[95% CI]

[95% CI]

[95% CI]

[95% CI]

Paracheck™-Pf

Microscopy

85.9 [80.8-90.1]

86.6 [81.1-91.0]

88.2 [83.2-92.1]

84.1 [78.4-88.8]

Microscopy and PCR

85.7 [80.8–89.8]

86.0 [80.1–90.6]

89.3 [84.7-92.9]

81.5 [75.4-86.7]

SD Bioline AgPf

Microscopy

92.3 [88.1-95.4]

82.2 [76.2-87.2]

85.7 [80.8-89.8]

90.2 [85.0-94.1]

Microscopy and PCR

85.4 [80.5–90.7]

86.3 [80.5–9.7]

89.7 [85.1-93.2]

81.0 [74.8-86.3]

SD Bioline AgPf/Pan

Microscopy

92.3 [88.1-95.4]

81.2 [81.1-91.0]

85.0 [80.0-89.2]

90.1 [84.8-94.0]

 

Microscopy and PCR

88.2 [83.2–92.0%]

80.4 [74.3–85.5]

83.1 [77.7-87.6]

86.1 [80.5-90.7]