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Table 1 Patterns of antimicrobial and associated resistances of the N. gonorrhoeae isolates detected in Switzerland during the study period a

From: Characterization of Neisseria gonorrhoeaeisolates detected in Switzerland (1998–2012): emergence of multidrug-resistant clones less susceptible to cephalosporins

Antibioticsb

No. and (%) of isolates

 

1998-2001 (n = 26)

2009-2012 (n = 34)

Resistant to ≥ 2 antibiotics:

14 (53.8)

31 (91.2)

-PEN and CIP

2 (7.7)

25 (73.5)

-PEN and AZT

3 (11.5)

8 (23.5)

-PEN and TET

14 (53.8)

28 (82.4)

-CIP and TET

2 (7.7)

23 (67.6)

-CIP and AZT

1 (3.8)

7 (20.6)

-AZT and TET

3 (11.5)

8 (23.5)

Resistant to ≥ 3 antibiotics (i.e., MDR isolates):

2 (7.7)

24 (70.6)

-PEN, CIP, and AZT

1 (3.8)

7 (20.6)

-PEN, CIP, and TET

2 (7.7)

23 (67.6)

-PEN, AZT, and TET

3 (11.5)

8 (23.5)

-CIP, AZT, and TET

1 (3.8)

7 (20.6)

Resistant to ≥ 4 antibiotics:

1 (3.8)

9 (26.5)

-PEN, CIP, AZT, and TET

1 (3.8)

7 (20.6)

-PEN, CIP, TET, and CFX

0 (0.0)

2 (5.9)

Resistant to 5 antibiotics (PEN, CIP, AZT, TET, and CFX)

0 (0.0)

2 (5.9)

  1. Note. PEN, penicillin; CIP, ciprofloxacin; AZT, azithromycin; TET, tetracycline; CFX, cefixime.
  2. aAll isolates were susceptible to ceftriaxone (CRO) and spectinomycin (SPE).
  3. b“Resistant” includes intermediate and resistant according to the EUCAST criteria [26].