Characteristics | Colistin N = 84 | Tigecycline N = 84 | p-value |
---|---|---|---|
Age | 63.8 (19.8) | 63.5 (17.7) | .92 |
Male | 63 (75) | 65 (77.4) | .67 |
APACHE II score | 21.6 (9.4) | 22.0 (8.8) | .99 |
Ventilator-associated pneumonia | 58 (69.1) | 60 (71.4) | .74 |
 Early onset VAP | 6 (10.3) | 4 (6.7) | .38 |
 Late onset VAP | 52 (90.0) | 56 (93.3) |  |
Length of hospital stay before enrollment | 29.5 (33.7) | 29.0 (30.1) | .92 |
Length of ICU stay before enrollment | 20.2 (29.6) | 18.5 (17.9) | .56 |
Duration of treatment | 14.0 (11.2) | 12.9 (9.3) | .51 |
Cardiovascular disease | 15 (17.9) | 15 (17.9) | 1.00 |
Diabetes mellitus | 24 (28.6) | 27 (32.1) | .59 |
 Insulin use | 20 (23.8) | 21 (25) | .85 |
Chronic kidney disease | 22 (26.2) | 22 (26.2) | 1.00 |
Liver cirrhosis | 2 (2.4) | 4 (4.8) | .41 |
Chronic pulmonary disease | 8 (9.5) | 8 (9.5) | 1.00 |
Malignancy | 2 (2.4) | 2 (2.4) | 1.00 |
Autoimmune | 3 (3.6) | 5 (6.0) | .48 |
Operation history | 40 (47.6) | 45 (53.6) | .44 |
Combination therapy | Â | Â | Â |
 Aminoglycoside | 1 (1.2) | 2 (2.4) | .56 |
 Carbapenem | 9 (10.7) | 9 (10.7) | 1.00 |
 Sulbactam | 1 (1.2) | 3 (3.6) | .32 |
Baseline creatine (mg/dL) | 1.70 (1.40) | 1.81 (1.60) | .50 |
Propensity score | 0.370 (0.130) | 0.370 (0.131) | .97 |