From: Multivariate analysis of prognostic factors in patients with pulmonary actinomycosis
Good outcome | Poor outcome | Pvalue | |
---|---|---|---|
(n = 59) | (n = 9) | ||
Gender, male (%) | 41 (69.5) | 6 (66.7) | 0.864 |
Mean age, years | 59.6 ± 11.3 | 51.0 ± 11.3 | 0.038 |
Size of parenchymal lesion | 3.7 (1.5-9.0) | 5.2 (2.6-7.0) | 0.093 |
Current smoker | 17/56 (30.4) | 3/8 (37.5) | 0.697 |
Heavy alcoholics | 7/52 (13.5) | 2/9 (22.2) | 0.609 |
Pulmonary comorbidity | 21 (35.6) | 4 (44.4) | 0.608 |
Hemoptysis | 32 (54.2) | 8 (88.9) | 0.071 |
Laboratory | |||
Normocytic normochromic anemia | 25 (42.4) | 5 (56.6) | 0.458 |
White blood cell, ×103/μL | 7.9 (2.6–33.1) | 8.0 (3.8–13.2) | 0.246 |
CRP, mg/dL | 1.5 (0.1–38.0) | 4.3 (0.1–6.72) | 0.726 |
Serum albumin, g/dL | 3.9 (1.2–4.7) | 3.8 (2.9–4.6) | 0.450 |
Systemic disease | |||
Diabetes mellitus | 11 | 1 | 1.000 |
Malignancy | 6 (75.0) | 2 (25.0) | 0.335 |
1 month after initial antibiotic therapy | |||
Responder | 38/41 (92.7) | 2/9 (22.2) | < 0.001 |
Non responder | 3/41 (7.3) | 7/9 (77.8) | |
Patients who did not use IV antibiotics | 25 (42.4) | 5 (55.6) | 0.493 |
Antibiotics duration | |||
IV antibiotics, day | 7 (2–21) | 7 (5–8) | 0.951 |
Initial therapy, months | 5.3 (0.4-13.0) | 10.2 (2.1–15.7) | 0.061 |
With rescue therapy, months | 5.3 (0.4–13.0) | 13.2 (5.9–33.1) | < 0.001 |