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Table 4 Comparison of pulmonary actinomycosis patients with good and poor outcomes

From: Multivariate analysis of prognostic factors in patients with pulmonary actinomycosis

  Good outcome Poor outcome Pvalue
(n = 59) (n = 9)
Gender, male (%) 41 (69.5) 6 (66.7) 0.864
Mean age, years 59.6 ± 11.3 51.0 ± 11.3 0.038
Size of parenchymal lesion 3.7 (1.5-9.0) 5.2 (2.6-7.0) 0.093
Current smoker 17/56 (30.4) 3/8 (37.5) 0.697
Heavy alcoholics 7/52 (13.5) 2/9 (22.2) 0.609
Pulmonary comorbidity 21 (35.6) 4 (44.4) 0.608
Hemoptysis 32 (54.2) 8 (88.9) 0.071
Laboratory    
 Normocytic normochromic anemia 25 (42.4) 5 (56.6) 0.458
 White blood cell, ×103/μL 7.9 (2.6–33.1) 8.0 (3.8–13.2) 0.246
 CRP, mg/dL 1.5 (0.1–38.0) 4.3 (0.1–6.72) 0.726
 Serum albumin, g/dL 3.9 (1.2–4.7) 3.8 (2.9–4.6) 0.450
Systemic disease    
 Diabetes mellitus 11 1 1.000
 Malignancy 6 (75.0) 2 (25.0) 0.335
1 month after initial antibiotic therapy    
 Responder 38/41 (92.7) 2/9 (22.2) < 0.001
 Non responder 3/41 (7.3) 7/9 (77.8)  
Patients who did not use IV antibiotics 25 (42.4) 5 (55.6) 0.493
Antibiotics duration    
 IV antibiotics, day 7 (2–21) 7 (5–8) 0.951
 Initial therapy, months 5.3 (0.4-13.0) 10.2 (2.1–15.7) 0.061
 With rescue therapy, months 5.3 (0.4–13.0) 13.2 (5.9–33.1) < 0.001