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Table 4 Comparison of pulmonary actinomycosis patients with good and poor outcomes

From: Multivariate analysis of prognostic factors in patients with pulmonary actinomycosis

 

Good outcome

Poor outcome

Pvalue

(n = 59)

(n = 9)

Gender, male (%)

41 (69.5)

6 (66.7)

0.864

Mean age, years

59.6 ± 11.3

51.0 ± 11.3

0.038

Size of parenchymal lesion

3.7 (1.5-9.0)

5.2 (2.6-7.0)

0.093

Current smoker

17/56 (30.4)

3/8 (37.5)

0.697

Heavy alcoholics

7/52 (13.5)

2/9 (22.2)

0.609

Pulmonary comorbidity

21 (35.6)

4 (44.4)

0.608

Hemoptysis

32 (54.2)

8 (88.9)

0.071

Laboratory

   

 Normocytic normochromic anemia

25 (42.4)

5 (56.6)

0.458

 White blood cell, ×103/μL

7.9 (2.6–33.1)

8.0 (3.8–13.2)

0.246

 CRP, mg/dL

1.5 (0.1–38.0)

4.3 (0.1–6.72)

0.726

 Serum albumin, g/dL

3.9 (1.2–4.7)

3.8 (2.9–4.6)

0.450

Systemic disease

   

 Diabetes mellitus

11

1

1.000

 Malignancy

6 (75.0)

2 (25.0)

0.335

1 month after initial antibiotic therapy

   

 Responder

38/41 (92.7)

2/9 (22.2)

< 0.001

 Non responder

3/41 (7.3)

7/9 (77.8)

 

Patients who did not use IV antibiotics

25 (42.4)

5 (55.6)

0.493

Antibiotics duration

   

 IV antibiotics, day

7 (2–21)

7 (5–8)

0.951

 Initial therapy, months

5.3 (0.4-13.0)

10.2 (2.1–15.7)

0.061

 With rescue therapy, months

5.3 (0.4–13.0)

13.2 (5.9–33.1)

< 0.001