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Table 1 In vitro activities of tested antimicrobial agents against 36 tigecycline non-susecptible K. pneumoniae isolates

From: Clinical and microbiological characteristics of tigecycline non-susceptible Klebsiella pneumoniaebacteremia in Taiwan

Antimicrobial agent MICarange (μg/mL) MIC50 b(μg/mL) MIC90 c(μg/mL) No. (%) of isolates susceptible
Tigecycline 3-32 6 8  
Ciprofloxacin <0.25 to >4 2 >4 15 (42)
Levofloxacin 0.5 to >8 >8 >8 14 (39)
Ampicillin-sulbactam 8 to >32 >32 >32 2 (6)
Piperacillin-tazobactam* 8 to >128 32 >128 12 (48)
Cefazolin <1 to >64 >64 >64 13 (36)
Ceftriaxone <1 to >64 <1 >64 21 (58)
Ceftazidime <1 to >64 16 >64 16 (44)
Cefepime <1 to >64 <1 >64 23 (64)
Amikacin <2 to >64 <2 16 33 (92)
Gentamicin <1 to >16 <1 >16 22 (61)
Ertapenem <0.5 to >8 <0.5 4 28 (78)
Imipenem <0.25 to 4 <1 <1 34 (94)
  1. aMIC: minimal inhibitory concentration.
  2. bMIC50: MIC for 50% of isolates.
  3. cMIC90: MIC for 90% of isolates.
  4. *Total number is 25 because 11 patients did not undergo the MIC test.