Table 1 In vitro activities of tested antimicrobial agents against 36 tigecycline non-susecptible K. pneumoniae isolates
Antimicrobial agent | MICarange (μg/mL) | MIC50 b(μg/mL) | MIC90 c(μg/mL) | No. (%) of isolates susceptible |
|---|---|---|---|---|
Tigecycline | 3-32 | 6 | 8 | |
Ciprofloxacin | <0.25 to >4 | 2 | >4 | 15 (42) |
Levofloxacin | 0.5 to >8 | >8 | >8 | 14 (39) |
Ampicillin-sulbactam | 8 to >32 | >32 | >32 | 2 (6) |
Piperacillin-tazobactam* | 8 to >128 | 32 | >128 | 12 (48) |
Cefazolin | <1 to >64 | >64 | >64 | 13 (36) |
Ceftriaxone | <1 to >64 | <1 | >64 | 21 (58) |
Ceftazidime | <1 to >64 | 16 | >64 | 16 (44) |
Cefepime | <1 to >64 | <1 | >64 | 23 (64) |
Amikacin | <2 to >64 | <2 | 16 | 33 (92) |
Gentamicin | <1 to >16 | <1 | >16 | 22 (61) |
Ertapenem | <0.5 to >8 | <0.5 | 4 | 28 (78) |
Imipenem | <0.25 to 4 | <1 | <1 | 34 (94) |