Percentages of doses followed by drowsiness (A), fever (B), irritability (C), and loss of appetite (D) of any intensity and grade 3 intensity reported during the 4-day post-vaccination period (total vaccinated cohort). Footnote: PHiD-CV group= infants vaccinated with PHiD-CV co-administered with DTPa-HBV-IPV/Hib at 2, 3, and 4 months of age. Control group= infants vaccinated with DTPa-HBV-IPV/Hib at 2, 3, and 4 months of age. Grade 3 symptoms: drowsiness if it prevented normal activity, fever if axillary temperature was >39.5°C, irritability if the infant was crying and could not be comforted or if it prevented normal activity, and loss of appetite if the infant did not eat at all. Error bars indicate 95% confidence intervals.