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Table 2 Demographics and clinical characteristics, by co-receptor tropism

From: High prevalence of CXCR4 usage among treatment-naive CRF01_AE and CRF51_01B-infected HIV-1 subjects in Singapore

FPR Criteria

FPR = 10

FPR = 5.75

Patient characteristics

CXCR4 (n=44), n (row %)

R5 (n=66), n (row %)

P-value

CXCR4 (n=35), n (row %)

R5 (n=75), n (row %)

P-value

Median age (median, IQR)

36.9 [28.8–45.4]

36.4 [27.6–44.6]

0.665

39.7 [29.4–45.4]

35.6 [27.6–45.0]

0.539

Male gender

38 (39.1)

59 (61.0)

0.765

30 (30.9)

67 (69.1)

0.752

Ethnicity

      

Chinese

34 (77.3)

54 (81.8)

0.630

27 (77.1)

61 (81.3)

0.617

Non-Chinese

10 (22.7)

12 (18.2)

 

8 (22.9)

14 (18.7)

 

Transmission risk

      

Heterosexual

20 (45.5)

30 (45.5)

0.945

15 (42.9)

36 (48.0)

0.502

MSM

23 (52.3)

33 (50.0)

 

14 (40.0)

32 (42.7)

 

Othersa

1 (3.0)

3 (4.5)

 

6 (17.1)

7 (9.3)

 

CD4 count at presentation (median, IQR)

226 [32–402]

333 [200–462]

0.013

219 [35–336]

333 [189–470]

0.025

Evidence of recent seroconversion(n=25)

      

Subtype B

2 (8.0)

4 (16.0)

0.011

1 (4.0)

5 (20.0)

0.007

CRF01_AE

3 (12.0)

10 (40.0)

 

3 (12.0)

10 (40.0)

 

CRF51_01B

5 (2.0)

0 (0.0)

 

5 (20.0)

0 (0.0)

 

Othersc

0 (0.0)

1 (4.0)

 

0 (0.0)

1 (4.0)

 
  1. Abbreviations: IQR, interquartile range; MSM, men who have sex with men; FPR, false-positive rate.
  2. a Blood transfusion, intravenous drug use (IVDU), bisexual.
  3. b Other subtypes: CRF02_AG, CRF34_01B, CRF07_BC, CRF15_01B.
  4. c Other subtypes: CRF33_01B.