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Table 2 Demographics and clinical characteristics, by co-receptor tropism

From: High prevalence of CXCR4 usage among treatment-naive CRF01_AE and CRF51_01B-infected HIV-1 subjects in Singapore

FPR Criteria FPR = 10 FPR = 5.75
Patient characteristics CXCR4 (n=44), n (row %) R5 (n=66), n (row %) P-value CXCR4 (n=35), n (row %) R5 (n=75), n (row %) P-value
Median age (median, IQR) 36.9 [28.8–45.4] 36.4 [27.6–44.6] 0.665 39.7 [29.4–45.4] 35.6 [27.6–45.0] 0.539
Male gender 38 (39.1) 59 (61.0) 0.765 30 (30.9) 67 (69.1) 0.752
Ethnicity       
Chinese 34 (77.3) 54 (81.8) 0.630 27 (77.1) 61 (81.3) 0.617
Non-Chinese 10 (22.7) 12 (18.2)   8 (22.9) 14 (18.7)  
Transmission risk       
Heterosexual 20 (45.5) 30 (45.5) 0.945 15 (42.9) 36 (48.0) 0.502
MSM 23 (52.3) 33 (50.0)   14 (40.0) 32 (42.7)  
Othersa 1 (3.0) 3 (4.5)   6 (17.1) 7 (9.3)  
CD4 count at presentation (median, IQR) 226 [32–402] 333 [200–462] 0.013 219 [35–336] 333 [189–470] 0.025
Evidence of recent seroconversion(n=25)       
Subtype B 2 (8.0) 4 (16.0) 0.011 1 (4.0) 5 (20.0) 0.007
CRF01_AE 3 (12.0) 10 (40.0)   3 (12.0) 10 (40.0)  
CRF51_01B 5 (2.0) 0 (0.0)   5 (20.0) 0 (0.0)  
Othersc 0 (0.0) 1 (4.0)   0 (0.0) 1 (4.0)  
  1. Abbreviations: IQR, interquartile range; MSM, men who have sex with men; FPR, false-positive rate.
  2. a Blood transfusion, intravenous drug use (IVDU), bisexual.
  3. b Other subtypes: CRF02_AG, CRF34_01B, CRF07_BC, CRF15_01B.
  4. c Other subtypes: CRF33_01B.