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Table 2 ST distribution among serotype 19A isolates from IPD in German children, before and after introduction of pneumococcal conjugate vaccine

From: Epidemiology of serotype 19A isolates from invasive pneumococcal disease in German children

CC

Before vaccination

After vaccination

 
 

STs

n=

%

STs

n=

%

p-value

473

3301, 3344

2

3.5

 

0

0

0.1287

2699

2699

1

1.8

 

0

0

0.3608

3111

6968

1

1.8

 

0

0

0.3608

group of two (5480)

1565

1

1.8

 

0

0

0.3608

group of two (5954, 6967)

5954(3), 6967

4

7.0

 

0

0

0.0158

group of two (8025)

6970

1

1.8

 

0

0

0.3608

singleton

1587

1

1.8

 

0

0

0.3608

singleton

1546

1

1.8

 

0

0

0.3608

singleton

1007

1

1.8

 

0

0.0

0.3608

15

423(2), 1201(3), 3546, 6975

7

12.3

1201(3), 15

4

4.0

0.0582

63

1621(1+1)

2

3.5

63(3)

3

3.0

1.0000

156

165

1

1.8

172, 277(2), 1349

4

4.0

0.6545

177

193, 6966

2

3.5

193(3), 3863

4

4.0

1.0000

199

199(7), 416(5), 667(3), 1756(3)

18

31.6

199(10), 416(3+7), 667(4), 1756(5), 2220

30

29.7

0.5899

230

230(3), 276, 1611(5), 6969, 6974

11

19.3

276(2+2), 319(4), 1611(5), 2013(3), 6972, 6976

18

17.8

0.8329

432

1848(2)

2

3.5

1848(2)

2

2.0

0.6199

group of two (2668)

6973

1

1.8

6973

1

1.0

0.5358

81

  

0

81

1

1.0

1.0000

320

  

0

320(5), 2432, 3259

7

6.9

0.0496

733

  

0

733

1

1.0

1.0000

994

  

0

994(14), 4197, 6978

16

15.8

0.0006

group of two (2653)

  

0

482(6)

6

5.9

0.0880

singleton

  

0

5204(3)

3

3.0

0.5537

singleton

  

0

8031

1

1.0

1.0000

total

 

57

100

 

101

100

 
  1. MDR isolates are indicated in bold. P-values from Fisher’s exact test, bold numbers are considered statistically significant (p<0.05).