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Table 4 NS1 sequence characteristics and positive selection analysis results

From: Performance of commercial dengue NS1 ELISA and molecular analysis of NS1 gene of dengue viruses obtained during surveillance in Indonesia

DENV serotype

DNA polymorphic site

Protein polymorphic site

pi (−)

pi (N)

pi (+)

DENV-1 (n = 21)

190

30

93.6%

2.6%

3.7%

DENV-2 (n = 6)

58

7

NA

NA

NA

DENV-3 (n = 17)

119

22

96.8%

1.7%

1.4%

DENV-4 (n = 4)

38

5

NA

NA

NA

  1. Note:
  2. pi (−): proportion of sites undergoing strong constraining selection.
  3. pi (N): proportion of sites undergoing neutral selection.
  4. pi (+): proportion of sites undergoing strong positive selection.
  5. NA: not applicable due to inadequate sample size.