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Table 4 Different antigens elicit differently enduring IgG responses

From: Natural antibody response to Plasmodium falciparum merozoite antigens MSP5, MSP9 and EBA175 is associated to clinical protection in the Brazilian Amazon

rAntigens

p < (T0 > T30)

p < (T30 > T60)

MSP1bl2_RO33

0.028

0.015

MSP3_3D7-like

0.022

0.033

 

p < (T0 < T30)

p < (T30 > T60)

MSP1bl2_MAD20

NS

0.028

MSP1bl2_K1

NS

0.043

MSP2_FC27

NS

0.018

MSP7

0.05

0.025

 

p < (T0 < T30)

p < (T30 > T60)

MSP2_IC1-69

0.043

NS

MSP2_IC1-I4

0.026

NS

MSP6

0.011

NS

 

p < (T0 > T30)

p < (T30 > T60)

MSP119

NS

NS

MSP4

NS

NS

MSP5

NS

NS

MSP9

NS

NS

MSP10 (3 alleles)

NS

NS

AMA1(2 peptides)

NS

NS

EBA140

NS

NS

EBA175

NS

NS

EBA181

NS

NS

  1. The significance of differences in the longevity of the humoral response in 13 serial samples (at 0, 30 and 60 days) is shown. For example, T0 > T30 means that the average of RI values decreased at time point 30. NS means statistically not different (Wilcoxon signed rank test). See also Additional file 2: Figure S5 for reactivity indices at time points 0, 30 and 60.