Natural antibody response to Plasmodium falciparum merozoite antigens MSP5, MSP9 and EBA175 is associated to clinical protection in the Brazilian Amazon

Table 1 Variables associated with the history of exposure to malaria parasites in general and to P. falciparum

Variables	Number of individuals (A/S)	Range	Median in whole sample	25%-75% percentiles whole sample	Median from A group	25%-75% percentiles from A group	Median from S group	25%-75% percentiles from S group
Age (y)	51 (24/27)	4-84	24	15-40.5	28	16-53	22	13-34
TLEA (y)	51 (24/27)	4-83	22.5	14-40.5	27	15-53	21	13-33
TLSA (y)	51 (24/27)	0-60	10	4.75-23.25	10	4-28	9	5-20
NPEF	47 (23/24)	0-30	4	2-5	4	1-8	3	2-5
NAR	51 (24/27)	0-26	13	7-16	14	6-18	13	7-14
TLSE (y)	48 (24/24)	0-30	1	1-3.5	2	1-14	1	1-1

Shown are the parameters symptomatic (S), asymptomatic (A), year (y), time of living in endemic area (TLEA), time of living in the same address (TLSA), number of previous episodes of falciparum infection (NPEF), number of recombinant antigens recognized (NAR) and time since the last symptomatic episode (TLSE). Note that some information could not be obtained from the participants leading to varying values in column 2.

ISSN: 1471-2334