|
Serious morbidity
| | | | | | | |
|
Overall
| | | | | | |
10-2
|
|
Events, n (Time at risk/100 PY)
|
58
|
(348)
|
49
|
(474)
|
85
|
(850)
| |
|
Incidence/100 PY (95% CI)
|
16.7
|
(12.4-20.9)
|
10.4
|
(7.5-13.3)
|
10.0
|
(7.9-12.1)
| |
|
WHO stage III or IV events
| | | | | | |
0.40
|
|
Events number (Time at risk/100 PY)
|
13
|
(391)
|
15
|
(549)
|
21
|
(1009)
| |
|
Incidence/100 PY (95% CI)
|
3.1
|
(1.3-4.8)
|
2.7
|
(1.4-4.1)
|
2.1
|
(1.2-3.0)
| |
|
ANRS grade 3 or 4
| | | | | | |
0.60
|
|
Events number (Time at risk/100 PY)
|
11
|
(392)
|
10
|
(558)
|
24
|
(1022)
| |
|
Incidence/100 PY (95% CI)
|
2.8
|
(1.2-4.5)
|
1.8
|
(0.7-2.9)
|
2.4
|
(1.4-3.3)
| |
|
Confirmed malaria
| | | | | | |
2.10-2
|
|
Events number (Time at risk/100 PY)
|
6
|
(381)
|
15
|
(529)
|
42
|
(968)
| |
|
Incidence/100 PY (95% CI)
|
1.6
|
(0.3-2.8)
|
2.8
|
(1.4-4.3)
|
4.3
|
(3.0-5.7)
| |
|
Other events*
| | | | | | |
7.10-2
|
|
Events number (Time at risk/100 PY)
|
13
|
(387)
|
9
|
(562)
|
15
|
(1060)
| |
|
Incidence/100 PY (95% CI)
|
3.4
|
(1.5-5.2)
|
1.6
|
(0.6-2.7)
|
1.4
|
(0.7-2.1)
| |
|
Death
| | | | | | |
10-4
|
|
Events number (Time at risk/100 PY)
|
26
|
(399)
|
13
|
(575)
|
8
|
(1100)
| |
|
Incidence/100 PY (95% CI)
|
6.5
|
(4.0-9.0)
|
2.3
|
(1.0-3.5)
|
0.7
|
(0.2-1.2)
| |
|
Lost to follow-up
| | | | | | |
10-4
|
|
Events number (Time at risk/100 PY)
|
40
|
(415)
|
47
|
(596)
|
41
|
(1138)
| |
|
Incidence/100 PY (95% CI)
|
9.6
|
(6.7-12.6)
|
7.9
|
(5.6-10.1)
|
3.6
|
(2.5-4.7)
| |
|
Attrition
| | | | | | |
10-4
|
|
Events number (Time at risk/100 PY)
|
66
|
(412)
|
70
|
(592)
|
49
|
(1132)
| |
|
Incidence/100 PY (95% CI)
|
16.0
|
(12.1-19.9)
|
11.8
|
(9.1-14.6)
|
4.3
|
(3.1-5.5)
| |
