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Table 1 Clinical characteristics of 560 HIV-infected patients with early syphilis

From: Predictors of serological failure after treatment in HIV-infected patients with early syphilis in the emerging Era of universal antiretroviral therapy use

Characteristic No. (%)
Age, median year [IQR] 40 [34,45]
Male sex 556 (99)
Race  
 Hispanic 249 (44)
 White 214 (38)
 Black 62 (11)
 Other/Unknown 35 (6)
MSM 541 (96)
Methamphetamine use 191 (34)
Hepatitis B or C 115 (21)
Syphilis history 287 (51)
Other STDa 419 (75)
Median RPR titers [IQR] 1:64 [1:32,1:128]
 <1:32 134 (24)
 ≥1:32 426 (76)
ART 486 (87)
CD4 T-cell count  
 Median CD4 T-cell count, cells/ml [IQR] 491 [345,683]
 <350 cells/mL 144 (26)
 ≥350 cells/mL 415 (74)
HIV RNA  
 Median HIV RNA level, copies/ml [IQR] ND [ND,631]
 Not detectableb 400 (72)
 Detectable 160 (28)
Early syphilis stage  
 Primary 77 (14)
 Secondary 146 (26)
 Early latent 337 (60)
Treatment regimen  
 3 doses of benzathine penicillin 434 (78)
 1 dose of benzathine penicillin 47 (8.4)
 Doxycycline 78 (14)
 Azithromycin 1 (0.2)
  1. Data are number (%) of patients, unless otherwise indicated. IQR, interquartile range; MSM, men who have sex with men; RPR, rapid plasma regain test; STD, sexually transmitted disease; HIV, human immunodeficiency virus; DM, diabetes mellitus; ART, combination antiretroviral therapy; ND, not detectable.
  2. aOther STD include documented Neisseria gonorrhoeae, chlamydia trachomatis, herpes, and genital warts.
  3. bDefined as <400 copies/mL.