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Table 3 Treatment outcomes of ASAQ, AL and DHAPQ at day 35 and day 42

From: Monitoring the efficacy and safety of three artemisinin based-combinations therapies in Senegal: results from two years surveillance

Outcomes

Uncorrected

PCR-corrected

 

DHAPQ (N = 148)

AL (N = 162)

ASAQ (N = 160)

p value

DHAPQ (N = 148)

AL (N = 162)

ASAQ (N = 160)

p value

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

Day 35

        

Late parasitological failure

1/148

1/162

2/160

 

00

00

1/160 (0.625%)

 

(0.67%)

(0.62%)

(1.25%)

ACPR

147/148

161/162

158/160

0.79

148/148

162/162

159/160

0.37

(99.33%)

(99.38%)

(98.75%)

 

(100%)

(100%)

(99.375%)

[85.1-99.9]

[85.7-99.9]

[86.2-99.9]

 

[84.5-99.9]

[85.2-99.9]

[85.6-99.9]

Day 42

DHAPQ (N = 134)

AL (N = 141)

ASAQ (N = 136)

 

DHAPQ (N = 134)

AL (N = 141)

ASAQ (N = 136)

 

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

Late parasitological failure

1/134

4/141

4/136

 

00

00

1/136

 

(0.75%)

(2.84%)

(3%)

(0.73%)

ACPR

133/134

137/141

132/136

0.38

134/134

141/141

135/136

0.36

(99.25%)

(97.16%)

(97%)

(100%)

(100%)

(99.27)

[84.4-99.9]

[86.6-99.9]

[87.1-99.9]

[83.7-99.9]

[84.2-99.9]

[84.5-99.9]

  1. ACPR, Adequate Clinical and Parasitological Response; NA, Not Applicable.