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Table 3 Association studies performed on an independent cohort including as covariates the gender and the polymorphism one by one

From: Genetic susceptibility to Chagas disease cardiomyopathy: involvement of several genes of the innate immunity and chemokine-dependent migration pathways

CCC VS ASY
GENE Tag SNP Genotype groups Association test
CCL2 rs3760396 GG vs GA + AA p = 0.626; OR = 1.35; 95% CI: 0.40-4.55
  rs2857656 CC vs CG + GG p = 0.267; OR = 1.16; 95% CI: 0.89-1.51
  rs4586 TT vs TC + CC p = 0.128; OR = 1.25; 95% CI: 1.94-1.67
  rs3917891 CC vs CT + TT p = 0.127; OR = 1.42; 95% CI: 0.90-2.23
  rs2530797 AA vs AG + GG p = 0.007; OR = 1.46; 95% CI: 1.11-1.92
  rs991804 CC vs CT + TT p = 0.435; OR = 1.23; 95% CI: 0.73-2.09
TIRAP rs11220437 TT vs TC + CC p = 0.149; OR = 1.27; 95% CI: 0.92-1.75
  rs591163 GG + GA vs AA p = 0.154; OR = 1.32; 95% CI: 0.90-1.94
  rs8177352 AA vs AG + GG p = 0.278; OR = 1.20; 95% CI: 0.87-1.66
  rs8177375 AA vs AG + GG p = 0.256; OR = 1.22; 95% CI: 0.87-1.72
  rs8177376 AA vs AC + CC p = 0.037; OR = 1.36; 95% CI: 1.19-1.80
  rs17866704 TT vs TC + CC p = 0.051; OR = 1.32; 95% CI: 1.00-1.76
CCC with a left ventricular ejection fraction value under 0.4% VS ASY
GENE Tag SNP Genotype groups Association test
CCL2 rs3760396 GG vs GA + AA p = 0.392; OR = 1.84; 95% CI: 0.45-7.46
  rs2857656 CC vs CG + GG p = 0.499; OR = 1.10; 95% CI: 0.83-1.46
  rs4586 TT vs TC + CC p = 0.194; OR = 1.23; 95% CI: 0.90-1.67
  rs3917891 CC vs CT + TT p = 0.156; OR = 1.40; 95% CI: 0.88-2.24
  rs2530797 AA vs AG + GG p = 0.002; OR = 1.59; 95% CI: 1.19-2.13
  rs991804 CC vs CT + TT p = 0.876; OR = 1.05; 95% CI: 0.60-1.83
TIRAP rs11220437 TT vs TC + CC p = 0.265; OR = 1.21; 95% CI: 0.86-1.71
  rs591163 GG + GA vs AA p = 0.134; OR = 1.38; 95% CI: 0.91-2.10
  rs8177352 AA vs AG + GG p = 0.224; OR = 1.23; 95% CI: 0.88-1.73
  rs8177375 AA vs AG + GG p = 0.313; OR = 1.21; 95% CI: 0.84-1.74
  rs8177376 AA vs AC + CC p = 0.046; OR = 1.36; 95% CI: 1.05-1.85
  rs17866704 TT vs TC + CC p = 0.095; OR = 1.29; 95% CI: 0.96-1.74