Figure 3

Flow cytometric analysis for CD107a degranulation marker and IFN-γ production in CD8 ⁺ and CD4 ⁺ T cell subsets. The frequencies of CD107a and IFN-γ expressing cells were analyzed from CD8⁺ and CD4⁺ T cell subsets (A). The cells were stimulated with PPD and the percentages of CD8⁺ and CD4⁺ T cells expressing CD107a (B,C) and IFN-γ (D,E) are calculated after the subtraction of the corresponding results from non-stimulated cells. The horizontal bars represent the medians of the responses. TB, n = 13, LTBI, n = 5, Surg., n = 5, Part., n = 5, Mod., n = 5 (CD4⁺IFN-γ⁺ n = 4), BCG+, n = 5.