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Table 3 Risk factors for multidrug resistance in CoNS isolates among children admitted to the NICU in Brazil from July 2007 through May 2008

From: Molecular epidemiology of coagulase-negative Staphylococcus carriage in neonates admitted to an intensive care unit in Brazil

Variables

Incident cases of MDR CoNSa

RR

95% CI

Pvalue

ORb

95% CI

Pvalue

Yes

No

Sex

        

  Male

46

184

1.29

0.80-2.34

0.256

   

  Female

25

136

      

Antimicrobial use

        

  Yes

62

241

2.42

1.10-5.37

0.011

0.51

0.21-1.26

0.144

  No

6

65

      

Low birthweight

        

  Yes

43

162

1.26

0.88-2.09

0.162

   

  No

28

153

      

Age at hospitalization

        

  <24 hours

55

241

1.12

0.67-1.85

0.670

   

  ≥24 hours

16

80

      

Type of birth

        

  Caesarean

39

219

0.61

0.40-0.93

0.023

1.70

0.97-2.99

0.064

  Vaginal

32

97

      

CPAPc

        

  Yes

30

97

1.53

1.00-2.35

0.056

1.08

0.58-2.03

0.805

  No

38

208

      

Hospitalizationd

        

  Median

9

2

  

< 0.05

0.97

0.96-0.98

0.000

  Interquartile range

5-15

2-2

      
  1. aMultidrug-resistant (resistance to four or more classes of antimicrobials), coagulase-negative Staphylococcus.
  2. bOdds Ratio adjusted for age at hospitalization and sex.
  3. cContinuous positive airway pressure.
  4. dLength of hospitalization (days).