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Figure 3 | BMC Infectious Diseases

Figure 3

From: Chagas disease-specific antigens: characterization of epitopes in CRA/FRA by synthetic peptide mapping and evaluation by ELISA-peptide assay

Figure 3

Capacity of the (CRA-1, CRA-2 and FRA-4) synthetic peptides to discriminate between serums infected by T. cruzi and Leishmania in a ELISA. Chagasic (n = 31) and Leishmaniasis (n = 14) patient sera, and healthy individual sera (n = 11) were diluted 1:50 and evaluated in triplicates against the peptide sequences CRA-1 (AAKQKAAEAAAKQKAAEAC-biot), CRA-2 (AAKQRAAEAAAKQRAAEC-biot) and FRA-4 (ADRAFLDQKPERVPC-biot). All tests were considered significant (p < 0,001) and the cut-off values of 0.226 for CRA-1, 0.199 for CRA-2 and 0.254 for FRA-1 were calculated. Each point of the graphic represents the media of two experiments.

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BMC Infectious Diseases

ISSN: 1471-2334

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