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Table 1 Clinical outcome data of Voriconazole vs. LAmB for use in decision model [3]

From: Pharmacoeconomic evaluation of voriconazole vs. liposomal amphotericin B in empiric treatment of invasive fungal infections in Turkey

Variable

Voriconazole

LAmB

Fever with no baseline fungal infection

96.87%

98.58%

   Therapeutic success

25.37%

30.05%

   Therapeutic failure

74.63%

69.95%

    Mortality

11.00%

8.59%

    Breakthrough fungal infection

2.67%

7.22%

    Premature discontinuation

13.67%

9.62%

    Persistent fevera

72.67%

74.57%

Fever with baseline fungal infection

3.13%

1.42%

   Therapeutic success

46.15%

66.67%

   Therapeutic failure

53.85%

33.33%

  1. aThe number of patients with persistent fever was determined by subtracting the number of patients that failed therapy due to a reason other than persistent fever from the total number of patients that had therapeutic failure to either voriconazole or LAmB.