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Table 5 Immunological parameters of 84 patients with NTM lung disease and 47 non-NTM BE patients

From: Phenotypic, immunologic, and clinical characteristics of patients with nontuberculous mycobacterial lung disease in Korea

 

NTM lung disease patients N = 84

Non-NTM BE patients N = 47

P value

Positive RF

5 (6.0%)

11 (23.4%)

0.01

RF level (0–9.9 IU/mL)*, median (IQR)

16 (15,92)

18 (15,86)

0.88

Positive FANA

11 (13.1%)

2 (4.3%)

0.14

FANA titer, median (IQR)

40 (40,50)

60 (40,80)

0.74

Positive IGRA

38 (45.2%)

26 (55.3%)

0.28

Patients with low level of immunoglobulins

   

IgG

(700–1700 mg/dL)*

1 (1.2%)

0 (0%)

1.00

IgA

(90–400 mg/dL)*

3 (3.6%)

0 (0%)

0.55

IgM

(45–230 mg/dL)*

6 (7.1%)

4 (8.5%)

0.75

C3

(70–150 mg/dL)*

1 (1.2%)

1 (2.1%)

1.00

C4

(10–35 mg/dL)*

1 (1.2%)

1 (2.1%)

1.00

  1. Abbreviations: FANA fluorescent antinuclear antibody test, IGRA IFN-γ release assay, RF rheumatoid factor, NTM nontuberculous mycobacteria, BE bronchiectasis, IQR interquartile range.
  2. *Normal ranges.