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Table 4 Imipenem potency in the absence and presence of AML in 42 A. baumannii isolates

From: Effects of a combination of amlodipine and imipenem on 42 clinical isolates of Acinetobacter baumannii obtained from a teaching hospital in Guangzhou, China

Compound/combination of compounds MIC (μg/ml) No. susceptible (%) No. nonsusceptible (%)a Statistical analysisb
MICRange MIC50 MIC90 χ2-values P values
AML 40-320 80 160 - - - -
IPM 0.5-32 16 16 7 (16.7%) 35 (83.3%) - -
IPM +10 μg/ml AML 0.5-32 8 16 13 (31.0%) 29 (69.0%) 2.363 0.200
IPM +20 μg/ml AML 0.5-32 8 16 15 (35.7%) 27 (64.3%) 3.941 0.081
IPM +40 μg/ml AML <0.5-32 4 16 23 (54.8%) 19 (45.2%) 13.274 0.001
  1. MIC, minimum inhibitory concentration; MIC50 and MIC90, MICs for 50% and 90% of strains, respectively; anonsusceptible, including intermediate resistance; bstatistical analysis compared with the IPM group.