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Table 2 Underlying disorders and predisposing conditions in patients with infective endocarditis (IE)

From: Profile of infective endocarditis observed from 2003 - 2010 in a single center in Italy

  No. (%) of patients  
  TOTAL Native valve Prosthetic valve p
Current IV drug use 50 (26%) 35 (30%) 15 (21%) 0.2
Steroid therapy 5 (3%) 3 (3%) 2 (3%) 1
Previous IE 36 (19%) 12 (10%) 24 (34%) <0.0001
Health care associated IE* 54 (29%) 33 (28%) 21 (30%) 0.3
Congenital heart disease 6 (3%) 6 (5%) 0 0.09
Rheumatic heart disease 9 (5%) 8 (7%) 1 (1%) 0.2
Pacemaker 11 (6%) 2 (2%) 9 (13%) 0.003
Data are median [interquartile range] or numbers (%).
  1. *Health care associated IE: chronic IV access/hemodialysis: 7/189 (4%); invasive procedures before IE (dental, urological and gastrointestinal procedures): 7/189 (4%) hospitalized in an acute care hospital before IE 38/189 (20%); resident in a nursing home or in a long-term care facility 2/189 (1%).