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Table 1 General characteristics of 166 patients with infective endocarditis (IE)

From: Profile of infective endocarditis observed from 2003 - 2010 in a single center in Italy

  No. (%) of patients p
Characteristic TOTAL Native valve Prosthetic valve
(189 events, 166 patients) (118 events, 111 patients) (71 events, 55 patients)
Age (years), median [IQR] 57 [43–72] 53 [42–71] 66 [50–75] 0.01
Male gender 104 (63%) 72 (65%) 32 (58%) 0.4
Time from onset of symptoms to admission  
  < 7 days 69 (37%) 41 (35%) 28 (39%)  
  >7 and ≤21 days 42 (22%) 25 (21%) 17 (24%)
  > 21 days 55 (29%) 34 (29%) 21 (30%) 1
  NA 23 (12%) 18 (15%) 5 (7%)
Co-morbidities  
  Cancer 14 (7%) 13 (11%) 1 (1%) 0.01
  Hypertension 39 (21%) 21 (18%) 18 (25%) 0.2
  Acute/chronic renal failure 17 (9%) 6 (5%) 11 (15%) 0.02
  Ischemic cardiopathy 21 (11%) 9 (8%) 12 (17%) 0.05
  Diabetes mellitus 29 (15%) 17 (14%) 12 (17%) 0.6
  COPD 9 (5%) 4 (3%) 5 (7%) 0.2
  CLD 55 (29%) 41 (35%) 14 (20%) 0.03
  HIV infection 35 (19%) 27 (23%) 8 (11%) 0.05
     CD4 cells/μL [IQR] 268 [145–353] 248 [124–313] 447 [348–1814] 0.008
     HIV-RNA cp/mL (n 22)     
     <10000 14 (40%) 8 (30%) 6 (75%)  
     10000-100000 5 (14%) 4 (15%) 1 (13%) 0.11
     >100000 4 (11%) 4 (15%) 0  
     NA 12 (34%) 11 (41%) 1 (13%)  
     HAART at IE     
     No 21 (60%) 15 (56%) 6 (75%) 0.2
     Yes 14 (40%) 12 (44%) 2 (25%)  
Data are median [interquartile range] or numbers (%).  
  1. NA, Not available; COPD, Chronic obstructive pulmonary disease; CLD, Chronic liver disease; HAART, Highly active antiretroviral therapy.