Humoral and cellular responses to a non-adjuvanted monovalent H1N1 pandemic influenza vaccine in hospital employees

Table 2 Humoral response after pandemic H1N1 vaccination

	Hemagglutination inhibition		Microneutralization assays
	Pre-vaccination	Post-vaccination	Pre-vaccination	Post-vaccination
N	60	60	60	60
Seroprotection rate%^a	6.7	66.7^d	NA	NA
Seroconversion rate%^b	NA	48.3	NA	NA
GMT^c	6.8	64.9^d	10.7	288.4^d
GMT Fold-change	NA	9.5	NA	26.9

^aSeroprotection rate = percentage of subjects with hemagglutinin inhibition titers ≥ 1:40.
^bSeroconversion rate = percentage of subjects with pre-vaccination hemagglutinin inhibition titers ≤ 1:10 and post-vaccination titers ≥ 1:40.
^cGMT = geometric mean titer.
^dp ≤ 0.05 vs pre-vaccination.

ISSN: 1471-2334