Table 2 Sensitivity for the detection of different bacteria according to specimen transport method and by cycle threshold cut-off value
Cycle threshold cut off ≤40 | Cycle threshold cut off ≤36 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Bacterium | Mailed (Left nare) | Frozen (Right nare) | Mailed (Left nare) | Frozen (Right nare) | ||||||
Episodes +ve | Sensitivity% | 95% CI | Sensitivity% | 95% CI | Episodes +ve | Sensitivity% | 95% CI | Sensitivity% | 95% CI | |
S. pneumoniae | 87 | 78.2 | 68.0 – 86.3 | 97.7 | 92.0 – 99.7 | 72 | 84.7 | 74.3 – 92.1 | 93.1 | 84.5 – 97.7 |
H. influenzae | 87 | 69.0 | 58.1 – 78.5 | 97.7 | 91.9 – 99.7 | 66 | 77.3 | 65.3 – 86.7 | 95.5 | 87.3 – 99.1 |
S. aureus | 29 | 82.7 | 64.2 – 94.2 | 82.7 | 64.2 – 94.2 | 17 | 64.7 | 38.3 – 85.8 | 76.5 | 50.1 – 93.2 |
MRSA | 8 | 75 | 34.9 – 96.8 | 62.5 | 24.5 – 91.5 | 3 | 0 | - | 100 | - |
B. pertussis | 3 | 66.7 | 9.4 – 99.2 | 33.3 | 0.8 – 90.6 | 0 | - | - | - | - |
M. catarrhalis | 77 | 80.5 | 69.9 – 88.7 | 97.4 | 90.3 – 99.7 | 63 | 82.5 | 70.9 – 90.9 | 93.7 | 84.5 – 98.2 |
Any species | 117 | 82.2% | 73.6, 88.1 | 94.8% | 89.4, 98.1 | 96 | 85.4 | 76.7 – 91.7 | 93.8 | 86.9 – 97.7 |