Skip to main content

Advertisement

Table 2 Results of the final multivariate model of patient drug exposures and comorbidities and their association with hospitalized SSSTI

From: “Serious skin & soft tissue infections in rheumatoid arthritis patients taking anti-tumor necrosis factor alpha drugs: a nested case–control study”

Variable Case Control Odds Ratio 95% Adjusted p value
N = 97 N = 291 Confidence
Interval
Frequency (Percent) Frequency (Percent)
Anti-TNF drug exposure 19 (19.59) 53 (18.15) 1.107 0.604, 2.028 0.92
Diabetes mellitus 36 (37.11) 53 (18.15) 2.514 1.528, 4.134 <0.01
Prior SSSTI 26 (26.80) 17 (5.82) 5.729 2.870, 11.434 <0.01
  1. Multivariate adjustment for RA severity, diabetes mellitus, chronic kidney disease, chronic bronchitis, prior history of skin infection, pneumonia, discharge 3 months prior, prednisone use within 30 days of the index date and antibiotic use 90 days prior to the index. Age and race were also included in the initial multivariate model to assess potential confounding.