Table 2 IFN-γ production pre and post therapy in patients with cutaneous and mucosal leishmaniasis
From: Immunologic response and memory T cells in subjects cured of tegumentary leishmaniasis
Disease | Time of evaluation after therapy | IFN-gamma | p | |
|---|---|---|---|---|
(Median and range) | value | |||
Pre therapy | Post therapy | |||
Cutaneous | ||||
Leishmaniasis | ≤ 5 years | 3608 pg/ml | 34.5 pg/ml | 0.0313 |
(N = 6) | (288 – 9700 pg/ml) | (0 - 2228 pg/ml) | ||
Cutaneous | ||||
Leishmaniasis | 6 to 13 years | 1086 pg/ml | 89.5 pg/ml | 0.0107 |
(N = 14) | (433 – 3873 pg/ml) | (0 – 2152 pg/ml) | ||
Mucosal | ||||
Leishmaniasis | ≤ 5 years | 4998 pg/ml | 12 pg/ml | 0.0039 |
(N = 9) | (529 – 41860 pg/ml) | (0 – 2769 pg/ml) | ||
Mucosal | ||||
Leishmaniasis | 6 to 15 years | 4520 pg/ml | 64 pg/ml | 0.0010 |
(N = 11) | (247 – 9660 pg/ml) | (0 – 2712 pg/ml) | ||