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Table 2 Details of ertapenem therapy

From: Evaluation of Ertapenem use with Impact Assessment on Extended-Spectrum Beta-Lactamases (ESBL) Production and Gram-Negative resistance in Singapore General Hospital (SGH)

  No. of Cases (%)
Indication for ertapenem use  
  Empiric 120 (13.2)
  Prophylaxis 7 (0.7)
  Culture-directed 779 (86.0)
Dose distribution  
  500 milligrams once daily 149 (16.5)
  1 gram every other day 16 (1.8)
  1 gram once daily 730 (80.6)
  1 gram stat 6 (0.6)
  Others^ 5 (0.5)
Median duration of therapy (days) (range) 8 (1 – 75)
Prescribed as outpatient antibiotic therapy (OPAT#) 185 (20.4)
Other antibiotic use in the same admission  
  Concurrent antibiotic therapy 566 (62.5)
  Previous antibiotic therapy 778 (85.9)
  Previous beta-lactam use * 754 (83.3)
  1. ^Others includes 250 milligrams once daily, 1 gram three times a week.#These patients only include those that continue OPAT from hospitalization.*Examples of beta-lactams include amoxicillin-clavulanic acid, ceftriaxone, cefepime and piperacillin-tazobactam.