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Table 2 Cytokine production by splenocytes of immunized Kunming mice after stimulation by toxoplasma lysate antigen a

From: Protective immunity against Toxoplasma gondiiinduced by DNA immunization with the gene encoding a novel vaccine candidate: calcium-dependent protein kinase 3

Groups Cytokine production (pg/ml)
IFN-γ IL-2 IL-4 IL-10 IL-12 (p70) IL-23
pVAX-CDPK3 612.11 ± 128.56** 263.79 ± 35.43** 32.42 ± 2.74** 870.12 ± 226.50** 129.63 ± 77.42** 87.59 ± 7.14**
pVAX I 34.91 ± 11.23 <15 <15 322.50 ± 179.17 15.14 ± 7.63 19.93 ± 22.65
PBS 36.34 ± 4.83 <15 18.96 356.13 ± 175.27 22.31 ± 4.40 27.12 ± 18.46
Blank control 47.28 ± 16.60 <15 <15 477.25 ± 87.53 22.65 ± 21.90 23.68 ± 14.13
  1. aSplenocytes from mice were harvested two weeks after the last immunization.
  2. **Statistically significant difference (P < 0.05).