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Table 1 Characteristics of the study participants

From: Potential association of pulmonary tuberculosis with genetic polymorphisms of toll-like receptor 9 and interferon-gamma in a Chinese population

Variables

Total (N = 600) n* (%)

PTB patients (N = 200) n* (%)

LTBI controls (N = 200) n* (%)

Healthy controls without MTB infection (N = 200) n* (%)

p for difference

Age

     

  18–19 years

48 (8.0)

16 (8.0)

15 (7.5)

17 (8.5)

 

  20–24 years

183 (30.5)

61 (30.5)

62 (31.0)

60 (30.0)

 

  25–29 years

68 (11.3)

23 (11.5)

23 (11.5)

22 (11.0)

 

  30–34 years

50 (8.3)

16 (8.0)

16 (8.0)

18 (9.0)

 

  35–39 years

60 (10.0)

20 (10.0)

20 (10.0)

20 (10.0)

 

  40–44 years

48 (8.0)

16 (8.0)

16 (8.0)

16 (8.0)

 

  45–49 years

65 (10.8)

22 (11.0)

22 (11.0)

21 (10.5)

 

  ≥50 years

78 (13.0)

26 (13.0)

26 (13.0)

26 (13.0)

 

Gender

     

  Male

333 (55.5)

111 (55.5)

111 (55.5)

111 (55.5)

 

  Female

267 (44.5)

89 (44.5)

89 (44.5)

89 (44.5)

 

Education

     

  ≤9 years

109 (18.2)

71 (35.5)

16 (8.0)

22 (11.0)

<0.01§

  10–12 years

139 (23.2)

55 (27.5)

31 (15.5)

53 (26.5)

<0.01&

  >12 years

352 (58.7)

74 (37.0)

153 (76.5)

125 (62.5)

 

Per capita income in the family

  <500 Yuan/Month

109 (18.2)

59 (29.5)

24 (12.0)

26 (13.0)

<0.01§

  500-2000 Yuan/Month

254 (42.3)

73 (36.5)

96 (48.0)

85 (42.5)

<0.01&

  ≥2000 Yuan/Month

237 (39.5)

68 (34.0)

80 (40.0)

89 (44.5)

 

Smoke status

     

  Never smoker

429 (71.5)

131 (65.5)

146 (73.0)

152 (76.0)

0.10§

  Former smoker

72 (12.0)

38 (19.0)

23 (11.5)

11 (5.5)

<0.01&

  Current smoker

99 (16.4)

31 (15.5)

31 (15.5)

37 (18.5)

 

Current alcohol drinking

     

  No

236 (39.4)

79 (39.5)

86 (43.2)

71 (35.5)

0.45§

  Yes

363 (60.0)

121 (60.5)

113 (56.8)

129 (64.5)

0.41&

BMI

     

  ≤18.5 (underweight)

78 (12.2)

42 (21.0)

17 (8.5)

14 (7.0)

<0.01§

  18.5-25 (normal)

412 (68.7)

146 (73.0)

128 (64.0)

138 (69.0)

<0.01&

  >25 (overweight)

115 (19.2)

12 (6.0)

55 (27.5)

48 (24.0)

 

Is there TB patient in the family

  No

550 (91.8)

179 (89.9)

185 (92.5)

186 (93.0)

0.37§

  Yes

49 (8.2)

20 (10.1)

15 (7.5)

14 (7.0)

0.28&

Number of scars by BCG vaccination

  0

242 (40.3)

131 (65.5)

66 (33.0)

45 (22.5)

<0.01§

  1

309 (51.5)

60 (30.0)

117 (58.5)

132 (66.0)

<0.01&

  ≥2

49 (8.2)

9 (4.5)

17 (8.5)

23 (11.5)

 
  1. Abbreviations: BMI body mass index, LTBI latent M. tuberculosis infection, MTB Mycobacterium tuberculosis; PTB pulmonary tuberculosis, TB tuberculosis.
  2. *Sum may not always add up to total because of missing data.
  3. §p for difference between PTB patients and LTBI controls.
  4. &p for difference between PTB patients and Healthy controls without MTB infeciton.