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Table 1 Characteristics of the study participants

From: Potential association of pulmonary tuberculosis with genetic polymorphisms of toll-like receptor 9 and interferon-gamma in a Chinese population

Variables Total (N = 600) n* (%) PTB patients (N = 200) n* (%) LTBI controls (N = 200) n* (%) Healthy controls without MTB infection (N = 200) n* (%) p for difference
Age      
  18–19 years 48 (8.0) 16 (8.0) 15 (7.5) 17 (8.5)  
  20–24 years 183 (30.5) 61 (30.5) 62 (31.0) 60 (30.0)  
  25–29 years 68 (11.3) 23 (11.5) 23 (11.5) 22 (11.0)  
  30–34 years 50 (8.3) 16 (8.0) 16 (8.0) 18 (9.0)  
  35–39 years 60 (10.0) 20 (10.0) 20 (10.0) 20 (10.0)  
  40–44 years 48 (8.0) 16 (8.0) 16 (8.0) 16 (8.0)  
  45–49 years 65 (10.8) 22 (11.0) 22 (11.0) 21 (10.5)  
  ≥50 years 78 (13.0) 26 (13.0) 26 (13.0) 26 (13.0)  
Gender      
  Male 333 (55.5) 111 (55.5) 111 (55.5) 111 (55.5)  
  Female 267 (44.5) 89 (44.5) 89 (44.5) 89 (44.5)  
Education      
  ≤9 years 109 (18.2) 71 (35.5) 16 (8.0) 22 (11.0) <0.01§
  10–12 years 139 (23.2) 55 (27.5) 31 (15.5) 53 (26.5) <0.01&
  >12 years 352 (58.7) 74 (37.0) 153 (76.5) 125 (62.5)  
Per capita income in the family
  <500 Yuan/Month 109 (18.2) 59 (29.5) 24 (12.0) 26 (13.0) <0.01§
  500-2000 Yuan/Month 254 (42.3) 73 (36.5) 96 (48.0) 85 (42.5) <0.01&
  ≥2000 Yuan/Month 237 (39.5) 68 (34.0) 80 (40.0) 89 (44.5)  
Smoke status      
  Never smoker 429 (71.5) 131 (65.5) 146 (73.0) 152 (76.0) 0.10§
  Former smoker 72 (12.0) 38 (19.0) 23 (11.5) 11 (5.5) <0.01&
  Current smoker 99 (16.4) 31 (15.5) 31 (15.5) 37 (18.5)  
Current alcohol drinking      
  No 236 (39.4) 79 (39.5) 86 (43.2) 71 (35.5) 0.45§
  Yes 363 (60.0) 121 (60.5) 113 (56.8) 129 (64.5) 0.41&
BMI      
  ≤18.5 (underweight) 78 (12.2) 42 (21.0) 17 (8.5) 14 (7.0) <0.01§
  18.5-25 (normal) 412 (68.7) 146 (73.0) 128 (64.0) 138 (69.0) <0.01&
  >25 (overweight) 115 (19.2) 12 (6.0) 55 (27.5) 48 (24.0)  
Is there TB patient in the family
  No 550 (91.8) 179 (89.9) 185 (92.5) 186 (93.0) 0.37§
  Yes 49 (8.2) 20 (10.1) 15 (7.5) 14 (7.0) 0.28&
Number of scars by BCG vaccination
  0 242 (40.3) 131 (65.5) 66 (33.0) 45 (22.5) <0.01§
  1 309 (51.5) 60 (30.0) 117 (58.5) 132 (66.0) <0.01&
  ≥2 49 (8.2) 9 (4.5) 17 (8.5) 23 (11.5)  
  1. Abbreviations: BMI body mass index, LTBI latent M. tuberculosis infection, MTB Mycobacterium tuberculosis; PTB pulmonary tuberculosis, TB tuberculosis.
  2. *Sum may not always add up to total because of missing data.
  3. §p for difference between PTB patients and LTBI controls.
  4. &p for difference between PTB patients and Healthy controls without MTB infeciton.