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Table 3 Factors associated with 30-day mortality in patients with enterococcal bloodstream infections

From: Impact of vancomycin resistance on mortality in neutropenic patients with enterococcal bloodstream infection: a retrospective study

 

Unadjusted HR (95% CI)

Adjusted HR (95% CI)

Age, years

1.03 (0.99–1.06)

 

Male sex

1.00 (0.62–1.62)

 

Vancomycin resistance

1.38 (0.53–3.59)

0.75 (0.24–2.36)

SAPS II at the onset of BSI (per 1 point)

1.12 (1.08–1.17)

1.13 (1.08–1.18)

Underlying hematologic diseases

  

  AML

1.00

 

  ALL

0.78 (0.27–2.24)

 

  Others

2.29 (0.73–7.19)

 

Treatment for underlying diseases

  

  Chemotherapy

1.00

 

  SCT

1.33 (0.72–2.47)

 

Length of hospitalization, day

1.05 (1.02–1.09)

1.00 (0.98–1.02)

Duration of neutropenia before BSI, day

1.00 (0.98–1.02)

 

Severity of neutropenia

  

  ANC (<500/mm3)

1.00

 

  ANC (<100/mm3)

0.43 (0.10–1.86)

 

Delayed administration of adequate antibiotics (> 48 hours)

0.78 (0.30–2.04)

 
  1. Abbreviations: ALL acute lymphoblastic leukemia, AML acute myeloid leukemia, ANC absolute neutrophil count, BSI bloodstream infection, CI Confidence interval, HR Hazard ratio, ICU intensive care unit, SAPS II Simplified Acute Physiology Score, SCT stem cell transplantation, OR Odds ratio, VRE vancomycin-resistant enterococci, VSE vancomycin-susceptible enterococci.